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Biomedical subjects

W C Jordan

Publications and source records attributed to W C Jordan.

At least 37 records · Page 2Linked to original sources

Malaria and HIV.

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HIV Seropositivity↗

Chancroid: a review for the family practitioner.

Chancroid, as the name implies, is like a chancre. Unlike the painless chancre of syphilis, it is painful, darkfield negative, and does not respond to penicillin therapy. The number of cases have continued to rise in recent years. Because it can cause irreversible anatomical destruction, making the correct diagnosis is important and can prevent chronic morbidity.

Adult↗

Mann-Cavallo sign.

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Blood Pressure Determination↗

Clinical trial of doxycycline in the treatment of anorectal and oropharyngeal gonorrhea.

Twenty-one patients who presented to three sexually transmitted disease (STD) clinics in the south area of Los Angeles County were diagnosed to have anorectal or pharyngeal gonorrhea and gave a history of hypersensitivity of penicillin. Treatment with doxycycline, 300 mg initially, followed by 200 mg daily for six days was successful in all cases. None was found to have penicillinase producing gonorrhea (PPNG).

Clinical Trials as Topic↗

The efficacy of doxycycline vs tetracycline in treatment of gonorrhea in men.

In attempting to improve treatment of gonorrhea in men allergic to penicillin or in those who refused intramuscular (IM) treatment, a comparison of the test of cure rate of doxycycline vs tetracycline was done. Tests of cure were performed one week after treatment on culture positive patients only. Doxycycline proved to have a better test-of-cure rate, primarily because of patient compliance.

Doxycycline↗

The efficacy of penicillin regimen in treatment of women with culture positive gonorrhea.

In an attempt to improve treatment of women with noncomplicated gonorrhea, assessment revealed compliance to be a problem. Tests of cure rates were above those expected with oral ampicillin. A third regimen was instituted and compared with procaine penicillin and ampicillin. Three physicians participated, each using only one regimen. All tests of cure were done one week after treatment. Only culture positive cases were evaluated.The third regimen, 4.8 million units of aqueous procaine penicillin G (APPG) plus 1 gm probenecid po, followed the next morning by oral ampicillin, 3.5 gm po, with 1 gm probenecid po, proved to have a better test of cure rate. This provides an alternative in situations of poor patient compliance.

Administration, Oral↗

Lassa fever: response to an imported case.

In February, 1976, a Peace Corps worker returned to the United States from Sierra Leone with an undiagnosed illness later recognized as Lassa fever. To assess the risk of transmission and to contain a potential outbreak, we identified 552 contacts as having had exposure to the patient before the start of strict isolation procedures, and maintained intensive surveillance on these contacts for 21 days. At the end of the surveillance period, no illness had developed in contacts. One month later, a serologic survey among 29 of the contacts judged to be at high risk gave no evidence of infection. In response to the importation of this communicable and highly fatal disease, procedures for the isolation of the patient, the identification, surveillance and management of contacts and the handling of laboratory specimens were developed and implemented. These procedures could be adapted to future introductions of highly contagious diseases.

Adult↗