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Biomedical subjects

W Brzeziński

Publications and source records attributed to W Brzeziński.

9 recordsLinked to original sources

[Minor blunt abdominal trauma can be dangerous].

Four cases with apparently mild abdominal trauma were presented. Finally, all but one were operated. On laparotomy ruptured spleen was found in two patients, the third had hematoma of the ileal mesentery. The fourth patient with subcapsular kidney hematoma was treated conservatively. All patients had initially denied any abdominal trauma. Sonography seems to be the most reliable and non-invasive investigation in making the diagnosis.

Abdominal Injuries↗

[The use of radial artery for the revascularization of the amputated thumb].

We present one of several methods for revascularization of the replanted thumb. Index radial artery is prepared, transposed and anastomosed to pollicis princeps artery. Twenty-seven patients aged 12-67 operated between 1991 and 1997 due to total or subtotal thumb amputation were included in this study. The method was used in 6 of them. In 21 patients different methods were applied to restore thumb arterial circulation. Venous grafts were used in 5 cases, end to end anastomosis of the artery in 16 cases. Thumb necrosis occurred in 2 cases in the venous grafts group and in 5 cases in end to end group. All thumbs revascularized with index radial artery healed successfully. The method requires only one microanastomosis and the risk of thrombosis is relatively small. The method should be recommended in cases of large arterial defects as an alternative for venous grafting.

Adolescent↗

[Post-traumatic painful ulnar nerve compression syndrome treated by wrapping the nerve with the vein: preliminary report].

Three cases of post-traumatic painful ulnar nerve compression syndrome are presented. Previous treatment both conservative and surgical (neurolysis) proved unsatisfactory. The method described-wrapping of the nerve with the saphenous vein graft in the area of scarification-gave satisfactory outcome in 2 of 3 operated patients (significant resolution of pain and improvement of sensation) in one year follow-up. In one patient surgery failed. The method presented might be considered in refractory cases of painful nerve compression syndrome due to its entrapment within scarred tissue after injury or previous surgery.

Arm Injuries↗

[Not Available].

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History, Modern 1601-↗

[Not Available].

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General Surgery↗

Morphochemical study of brown adipose tissue during adrenal gland regeneration in the white rat.

The interscapular brown adipose tissue in male, white Wistar rats in the 1,3,6,15,30, and 60th day of regeneration of adrenals after their enucleation weas investigated. The tissue slides were stained with H and E, with Masson's triple stain and with Sudan B. The activity of the following dehydrogenses was evaluated: Succinic dehydrogenase, delta 5,3 beta-hydroxysteroid dehydrogenase and the activity of the following enzymes; monoaminooxidase (MAO), Alkaline phosphatase (AlPh) and acid phosphatase (AcPh) was studied. Between the first ad 30th day of regeneration of adrenals morphochemical changes were observed; a great number of cells with eosinophylic cytoplasm appeared and with minute vacuols in their cytoplasm, the blood vessels became more numerous and enlarged and the activity of the enzymes tested was enhanced, instead sudanophilia was weaken and the reaction of corticosteriods significantly intensified. The changes observed may indicate on an enhanced hormonal activity. The brown adipose tissue may function as an endocrine gland which supports the regenerating adrenals of the white rat, enables survival and preservation of homeostasis during the insufficiency of the adrenal cortex after adrenal enucleation. The initiation of the endocrine activity of the brown adipose tissue in the course of regeneration of the adrenals proceeds probably without the direct participation of catecholamines originating from the adrenals.

3-Hydroxysteroid Dehydrogenases↗

Monoclonal antibodies--why should surgeons be interested?

Many different monoclonal antibodies used experimentally and clinically are highly tumor-specific. Radiolabelling of these antibodies has been successfully accomplished. Immunoscintigraphy of primary and metastatic cancers has a reported sensitivity of 59-70%. However, in many studies, operative and histologic confirmation is lacking. Radioimmunoguided surgery is a promising new adjunctive technique for the surgical treatment of colorectal cancer. Its reported sensitivity ranges between 70 and 100% and specificity between 66 and 100%. In approximately one-third of patients with colorectal cancer, additional intraoperative information concerning the presence of subclinical tumors was gained using radioimmunoguided surgery. This system has the potential to assist the surgeon in performing complete resection of cancer and decrease the local recurrence rate. This could be of particular clinical importance for rectosigmoid tumors where the reported local recurrence rate is as high as 30%. Despite the advances made, many problems still need to be resolved. Radioimmunoguided surgery, however, has the potential to change the way surgery for colorectal cancer is being performed. It offers the possibility of improvement in patient survival.

Animals↗