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Biomedical subjects

W Brunner

Publications and source records attributed to W Brunner.

At least 37 records · Page 2Linked to original sources

[Investigation of inflammatory paranasal sinus diseases with scintigraphy (author's transl)].

In the course of inflammatory diseases affecting the paranasal sinuses, a number of complications may occur. One of those is the involvement of neighbouring skeletal portions. By this study evidence is given, that there is a high rate of inflammation, spreading to adjoining bone areas. This applis also to early stages and first manifestations. Especially in cases of surgery, complete recovery is rare. The pattern of chronic recurrent osteomyelitis may develop.

Adult

[The bronchial alveolar carcinoma as a solitary coin lesion].

Bronchiolo-alveolar carcinoma is a well-differentiated adenocarcinoma which starts as a peripheral solitary nodule and gradually spreads via the bronchi to give rise to a disseminated, diffusely infiltrative tumor. A series of 17 cases presenting with solitary nodules is reported. A long interval before operation did not adversely affect prognosis, provided the nodule remained relatively small and there were no lymph node metastases. Radical cure by resection was possible only with solitary nodules, but not with multinodular or infiltrative tumors. Prognosis was worse if lymph nodes were involved but not if there was intrapulmonary lymphatic invasion without spread to lymph nodes. Large solitary nodules shortened survival, especially if the radiographic diameter was greater than 5 cm. On the other hand, in four cases where evaluation was possible, the rate of growth had no effect on prognosis. Patients with positive cytology had shorter life expectancy since the tumor had already spread to the bronchi. Unexpectedly, cellular signs of malignancy had no influence on prognosis. Invasion of blood vessels, however, was a poor prognostic sign and was not observed in early cases or in patients with prolonged survival.

Adenocarcinoma

[The spontaneous, non-traumatic chylothorax. Therapy by means of pleurectomy and decortication].

Two cases of chronic spontaneus chylothorax were successfully treated by small thoracotomy with parietal pleurectomy or decortication after unsuccessful needle aspiration and intercostal tube drainage with suction. In the one case the chylous effusion occurred spontaneously 29 years after extrapleural pneumothorax. The tuberculosis was long cured. In the other, apparently idiopathic case, the chylothorax on the left side disappeared completely after pleurectomy. Six months later a chylous effusion appeared on the right side. Mediastinoscopy then revealed an oatcell carcinoma in lymph nodes without a primary pulmonary tumor. One year after radiotherapy the patient died in heart failure. No primary tumor was found. Residual chylothorax was present only on the right side.

Aged

[Effects of short time extreme hemodilution with and without hypothermia on hemodynamic and biochemical parameters in the pig (author's transl)].

Extreme hemodilution as "Total Body Washout" (TBW) is a feasible method for the clinical therapy of endo- or exogenous intoxication. This method was modified for a simple and quick setup. Landrace pigs were hemodiluted with a special heart-lung-machine. Within 4 minutes the hematocrit was lowered to less than 1%. The rectal temperature fell hereby in a normothermic group (n = 15) to 35, 1 +/- 1, 1 degrees C and in a hypothermic one (n = 13) to 31,1 +/- 1,3 degrees C. The TBW was followed by a total exchange transfusion. Most of the parameters that were studied did not show significant differences between cold and warm perfusion. The proceeding was well tolerated by the animals, they were observed up to 6 weeks. Disadvantages of initial surface cooling may be avoided by extreme hemodilution with exclusive extracorporal cooling, when cardiac arrest in hypothermia is intended.

Animals