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Biomedical subjects

W Booth

Publications and source records attributed to W Booth.

66 records · Page 4Linked to original sources
PubMed1987

The NIH legislators.

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National Institutes of Health (U.S.)↗
PubMed1987

AIDS and insects.

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Acquired Immunodeficiency Syndrome↗
PubMed1982

Evidence for a platelet membrane defect in the myeloproliferative syndromes.

Bleeding and abnormal platelet aggregation occur in patients with myeloproliferative disorders. In this study, twenty patients were examined, some sequentially, and a proportion found to have defective aggregation toward adrenaline, adenosine diphosphate (ADP), and collagen. In these seven patients, the abnormality in platelet response with defective collagen-induced [14C]serotonin release correlated with poor collagen-stimulated thromboxane B2 (TXB2) production. In contrast, five of these patients showed a normal threshold aggregation response to arachidonic acid. The combined results suggest that in these patients, there is a defect between receptor-stimulus coupling and the mobilization of arachidonic acid from membrane phospholipid.

Blood Platelets↗