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Biomedical subjects

W Bircks

Publications and source records attributed to W Bircks.

At least 145 records · Page 8Linked to original sources
PubMed1975

[Experiences in the treatment of acute renal failure following cardiovascular surgery (author's transl)].

After 9021 cardiovascular operations 210 patients developed acute renal failure. 140 (67%) out of this group died. The mortality rate of acute renal failure could be reduced from 80% (1958-1966) to 50% (1973-1974). Dialysis treatment should begin early and also in special cases, in which the cause of acute renal failure is not under control. Beyond optimal dialysis therapy common intensive care is important for the prognosis of acute renal failure, especially adaption of drugs to renal function (antibiotics and digitalis), high-caloric alimentation, consequent treatment of infections, strict balance of fluid and electrolytes.

Acute Kidney Injury↗
PubMed1975

[Banding for pulmonary artery and subsequent repair in large ventricular septal defect (author's transl)].

Banding of the pulmonary artery was performed in 233 children with large, non restrictive ventricular septal defects. The group of isolated large VSDs consisted of 95 patients, of whom 8 died (8,4 per cent). 32 patients were subjected to open-heart operation for closure of the VSD and debanding. In this "two-stage group" the mortality rate was 6,3 per cent. At the second operation the pulmonary artery always should be enlarged with a pericardial patch. Our recordings up to 6 1/2 years after correction show no gradients left in cases surgically treated in this manner. The time-interval between effective banding and debanding procedure may not be limited strictly; the subsequent operation however should be done within two or three years.

Age Factors↗
PubMed1975

[Letal rate and late complications following palliative surgery of transposition of the great arteria (author's transl)].

Between 1966 and 1973 145 palliative procedures were carried out on 110 infants with transposition of the great arteries. There were 23 early deaths (20.9 per cent). 85 per cent of the survivors were controlled till the end of 1974. Five late deaths and four cases of peripheral artery embolism were regarded. These complications, however, took place several years after palliation. The development of pulmonary hypertension doesn't seem to be as high as it is suspected sometimes. These results justify our conception, not to perform the Mustard-operation during the first two years of life.

Age Factors↗
PubMed1975

[Comparing studies on the influence of dopamine and orciprenaline on cardiac and renal function of patients after cardiac surgery (author's transl)].

Cardiac and circulatory function (cardiac output, stroke volume, heart rate, mean arterial pressure = MAP, total peripheral resistance = TPR), further renal function (PAH- and inulin clearance, filtration fraction, urinary excretion, renal sodium- and potassium excretion) were measured on 15 patients undergoing cardiac surgery to whom Dopamine and Orciprenaline were administered in increasing doses of 100 mug - up to 500 mug/min (Dopamine) and 10 mug - to 20 mug/min (Orciprenaline). An infusion of Dopamine up to 250 mug/min caused a dosis-related increase of the cardiac output up to 31% (2P less than 0.001) without essential increasing of the MAP and of the heart rate. Dopamine caused a decrease of the TPR up to 24%. Doses of Dopamine over 250 mug/min cause an increase of the MAP and of the heart rate without a real increase of the cardiac output. Renal function improved under increasing doses of Dopamine, effective renal plasma flow (ERPF) up to 74%, urinary excretion up to 130%, sodium and potassium excretion up to 60% respectively. After administering Orciprenaline in a dosis of 20 mug/min cardiac output increases up to 28%, MAP and heart rate up to 12% and 17% respectively. After the administration of Orciprenaline (20 mug/min) and Dopamine (500 mug/min) frequent extra systoles were observed without any increase of the cardiac output; MAP increased by 12%, TPR decreased by 16% after 20 mug/min of Orciprenaline. ERPF decreased slightly after Orciprenaline. Urinary excretion was reduced by a half.

Aminohippuric Acids↗
PubMed1975

[Findings of scanning microscopy studies and gas-transfer results in long-term perfusions using membrane oxygenators in animal experiment].

Twelve hours partial extracorporeal circulation using the GEDL was carried out in sheep with experimental pulmonary insufficiency. The maximal O2-transfer was 53,8 ccm/min/m2 membrane surface at blood flows of 2 and 3 1/min. The CO2-transfer was nearly 30 ccm/min/m2 if the pCO2 was within the normal range. There was evidence, that the O2-transfer decreases during prolonged perfusion. Scanning-electron-microscopic studies revealed a thickening of the membrane with protein and cell-fragments which were thought to be the reason for the observed decrease in O2-transfer.

Animals↗