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Biomedical subjects

W Berg

Publications and source records attributed to W Berg.

At least 73 records · Page 4Linked to original sources

Predictors of self-sufficiency for the mentally ill in long-term care.

A growing interest of mental health professionals is the community adjustment of former mental hospital patients. Recognition of the influence of environmental factors on adjustment has led to attempts to determine the specific environmental factors that are influential. The present study of 87 former mental hospital patients in long-term care indicates that the type of management practices used, together with the facility director's attitudes toward social services are major predictors of clients self-sufficiency. Implications for administrators, staff and consultants to long-term care facilities are noted.

Activities of Daily Living↗

Fluorescent staining of sialidases in polyacrylamide gel electrophoresis and ultrathin-layer isoelectric focusing.

Polyacrylamide gels were stained with the sialidase substrate 2'-(4-methylumbelliferyl)-alpha-D-N-acetylneuraminic acid showing the activity of Vibrio cholerae and Clostridium sordellii sialidases in the gels after electrophoresis. With this fluorogenic method minimum sialidase activities of 5 microU could be determined. The sensitivity of this staining is about 10,000-fold higher compared to protein-staining with Coomassie brilliant blue. For the visualization of other proteins than sialidases the specific sialidase staining could be followed by a protein-staining method in the same gel.

Chemical Phenomena↗

[Not Available].

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Academies and Institutes↗

International ring test to check the quality of urolith analyses.

In an international ring test, five mixtures of stone substances were analyzed with different methods in 29 selected stone analysis laboratories in 13 countries. Evaluation revealed very good analysis qualities especially for X-ray diffractometric and infrared techniques. The analytical skills of the investigators are confirmed by a mean standard of quality of 1.69 for all qualitative results determined. It would be possible to improve the diagnosis of urolithiasis by standardizing and centralizing stone analysis.

Calcium Phosphates↗

Possibilities of computing urine parameters as a means of classification of normals and patients suffering from calcium oxalate lithiasis.

By the use of simple quotients consisting of the lithogenic variables in the numerator and the litholytic ones in the denominator as well as of complex chemical and discriminant analytical computational use of urine parameters, it is possible to distinguish significantly between groups of control persons and recurrent calcium oxalate stone formers and to obtain a relative prediction concerning the risk of stone formation. In discriminant analytical computation, in our opinion, it is most convincing to make use of variables which have been checked multivariately concerning their separating properties with regard to their mutual correlations and their measure of indispensability.

Calcium Oxalate↗

[Effect of proteolytic enzymes, electrolytes and other factors on the crystallization of calcium oxalate in the urine].

On the basis of 18 discriminance-analytically balanced urine parameters of patients with recidive calcium-oxalate nephrolithiasis and control subjects without urological complaints, it is shown in this article that the concentration of proteolytic activity, of enzyme inhibitors, of acid mucopolysaccharides and inhibition indices do not give better separation between the control group and recidive calcium-oxalate lithiasis patients than the usually measured urine parameters.

Calcium Oxalate↗

[Are silicates only gravel stones?].

The presence of silicon dioxide in urinary calculi usually indicates the presence of artefacts. However in isolated cases infra-red and X-ray spectroscopy and electron-ray microanalysis have clearly demonstrated the presence of silicate in crystalline urinary sediment and as a phase of urinary calculi, probably as a result of overdoses of silicon preparations. A local silicon enrichment of up to 2% is certain in phosphate phases and makes an isomorphic incorporation of SiO4 ions probable.

Humans↗

[Criteria of usefulness for the standardized x-ray diffractometric urinary calculus analysis. Improvement in the quality of urinary calculus analysis by the establishment of uniform methodological assumptions in urinary calculus analysis laboratories. 1].

Urolith analysis by X-ray diffraction is centralized and standardized in the GDR. By setting up uniform methodological conditions the quality of analytical results can be markedly improved. The resulting analytical criteria of usefulness - precision, detection limits and correctness - meet the requirements of diagnostic reliability and guarantee therapeutic relevance.

Germany, East↗

[Evidence of improved quality of urinary calculus analysis using results of 7 surveys with external quality controls. Improvement in the quality of urinary calculus analysis by establishment of uniform methodological assumptions in urinary calculus analysis laboratories. 2].

Seven quality control surveys confirmed the usefulness of standardized urolith analysis by X-ray diffraction. A method is suggested for tabulating the results of the surveys, which permits qualitative comparison of participating analysis centres. Quality improved considerably after the introduction of the standardized instructions for analysis. The results of the survey with international participants clearly demonstrated the superiority of X-ray diffractometric urolith analysis over polarization microscopical, infrared spectroscopic, differential thermoanalytical and wet chemical analytical techniques.

Humans↗

Biological rhythmicity and crystallization--urine profiles and Se-studies on calcium oxalate stone genesis.

In profile urines from oxalate stone patients and normal persons the progress of concentration and excretion of 10 urine parameters was investigated. For the majority of lithogenic and litholytic urine substances, especially for oxalic acid, a day-and-night rhythm was proven. This may be transferred to a principle of zonary structure of weddellite crystals, explaining the periodically recurring change of weddellite layers of different dissolution resistances arising from different growth rates due to different concentrations of supersaturated urine.

Calcium↗

[Gel model for measuring crystallization inhibitor activity].

In an attempt to develop a method with the most favourable possible relationship of information gained to expenditure of material and time a simple way of measuring crystallisation inhibitor activity was developed. Calcium and oxalate ions are diffused against each other out of two opposite start holes in a layer of gel on a microscopic slide and form a strip of calcium oxalate crystals where they meet in the middle. The substances influencing crystallisation are allowed to diffuse into this central area. The density and extent of the calcium oxalate strips vary according to the inhibitory effect of the substances used. These differences were registered by means of photometric measurement for comparison against a control without any inhibitor added and an inhibition index was computed. Some of the best-known inhibitors were tested and also show a defined effect in this model. In physiological concentrations magnesium and citrate can be said to have particular importance. The range of inhibitory activities to be expected of human urine is covered by the present model.

Anthraquinones↗

[Personal experiences in the long-term treatment of cystine lithiasis with high-dose ascorbic acid].

We report on our experience with 9 cystine-lithiasis patients who were treated with large doses of ascorbic acid (5 g/day) for periods ranging from 6-27 months. We observed recidive lithogenesis in only 3 patients during this time. The influence of ascorbic acid on the excretion of cystine and oxalate in the urine is discussed. A lack of side effects and the significantly lower frequency of recidivation justify the further use of ascorbic as an alternative medication in cystine lithiasis.

Adult↗

[Experimental and clinical studies concerning the influence of natural substances on the crystallization of calcium oxalate (author's transl)].

Krapp-Hydroxyanthrachinone given orally will, in a dosage of 150-200 mg, inhibit the intra-renal crystallization of calcium oxalate in the rabbit kidney following Glyoxalate intoxication. This inhibition is increased considerably by Na-Cu-Chlorophylline. The mechanism of action of the inhibitor substances is a specific surface adsorption prohibiting formation of microliths. This can also be shown in precipitation experiments in vitro. The authors suggest a certain clinical use of a combination of the tested dye with vitamin B6, citrate and magnesium preparations.

Animals↗

[Stress and risk of urolith formation. I. The influence of stress on lithogenous urinary substances (author's transl)].

In the present work the influence of stress situations on the concentrations and excretions of lithogenous urinary substances (calcium, oxalic acid, uric acid) has been studied in defined urine portions of 10 calcium oxalate stone patients and 10 normal subjects and the results compared to those of 20 stone patients and 10 normal subjects without stress. Stress may be objectified in the given task. The increase of concentrations and excretions of lithogenous urinary substances indicates an enhanced risk of stone formation. Uric acid is discussed as an agent promoting the calcium oxalate crystallization. New insights on the calcium oxalate stone genesis are gained from the results.

Adult↗

The influence of magnesium chloride on blood and urine parameters in calcium oxalate stone patients.

The influence of magnesium chloride on various blood and urine parameters in calcium oxalate stone patients is studied. High dose magnesium therapy was found to increase urinary magnesium concentrations, whereas the oxalic acid concentration is reduced. The experiments support the statements on the role of magnesium in endogenous oxalic acid depression and the inhibition of the intestinal resorption. For urolith prevention it will be necessary to apply high magnesium doses of easily absorbable and well-tolerated medicaments.

Adult↗