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Biomedical subjects

W Bailey

Publications and source records attributed to W Bailey.

At least 73 records · Page 4Linked to original sources
PubMed1982

Patterns of contraceptive use in Kingston and St Andrew, Jamaica, 1970--1977.

The records of a sample of Family Planning acceptors were examined to identify those factors which influenced the choice of a contraceptive and the drop-out rate in the period 1970--1977 inclusive. It was found that although a full range of contraceptives was theoretically available, as the 1970s advanced the effective choice appeared to lie between the two hormonal contraceptives, medroxyprogesterene acetate (Depo Provera) and the oral contraceptive pill with family size being the deciding factor. The drop-out rate as also influenced by family size with nulliparous women showing the highest rate. Explanations for the drop-out rates and the percentage of single visits made to the clinics were sought through the utilization of partial correlations. In both cases the average distance between the acceptor's home and the clinic appeared to play a decisive role.

Adolescent↗
PubMed1978

Influence of acetaldehyde, dietary protein, carbon tetrachloride and butylatedhydroxytoluene on the toxicity of methylmercury in rats.

The influence of environmental or dietary factors on the toxicity of methylmercury (MeHg) was investigated due to possibilities that humans exposed to methylmercury may have been sensitized. Groups of 8 rats were exposed to 0, 20 or 40 ppm MeHg in a semisynthetic diet and fed 0.5% BHT, 5% protein (instead of 15%), or injected with 250 mg/kg CC14 or acetaldehyde. In control rats neurotoxicity occurred at 4 weeks and 9 weeks with 40 and 20 ppm MeHg, respectively. Mortality was observed at 6 weeks with 40 ppm and 1 rat died in week 9 with 20 ppm MeHg. Acetaldehyde injected rats died at week 4 and 6 when fed 40 or 20 ppm MeHg. Neurotoxicity was observed in week 3 and 5 in these groups, respectively. Treating rats with the low protein or BHT accelerated neurotoxicity and mortality by 1 week with 40 ppm MeHg. These agents had killed all test animals within 7 weeks at 20 ppm MeHg. Neither acetaldehyde nor BHT influenced 0 ppm MeHg controls while 5% protein induced precipitous weight loss. In the case of CC14, the rats lived longer in combination experiments than one would have expected from the individual treatments.

Acetaldehyde↗
PubMed1978

Inhibition of mitochondrial DNA synthesis by aflatoxin B1 and dimethylnitrosamine.

The acute and subchronic effects of aflatoxin B1 and dimethylnitrosamine (DMN) on in vitro incorporation of thymidine-3H into DNA (mt-DNA) from mouse liver mitochondria were studied after single injection or after one month or three months of weekly injection. Both carcinogens induced 50% decreases in mt-DNA synthesis acutely, with a 50% decrease in synthesis of high molecular weight mt-DNA. Subchronic administration of aflatoxin B1 inhibited mt-DNA synthesis by 54% with elution profiles similar to the controls. DMN showed only a 29% inhibition of mt-DNA synthesis at one month increasing to 55% at three months.

Aflatoxins↗
PubMed1977

Leiomyomas of the rectum and anal canal: report of six cases and review of the literature.

Since 1872, 168 rectal leiomyomas have been reported in the world literature. Their incidence, therefore, is very low. It is estimated that one leiomyoma may be seen for every 2,000 or more rectal tumors. Those leiomyomas located in the anal canal and sphincter are the rarest. A case is reported here that appears to be the eleventh in such a location. The incidence of these lesions is highest between the ages of 40 and 59 years. Most patients have a combination of symptoms rather than a single one, the most frequent of these being the presence of a mass, bleeding, and constipation. Almost always, the chain of events that leads to the diagnosis starts when the tumor is discovered by digital examination of the rectum. The lack of reliable criteria of malignancy and the marked tendency to recur shown by these tumors are the two main problems the surgeon faces when selecting the operative procedure to be used. We believe that those tumors with an original size of 5 cm or more in largest diameter are the ones that have shown the highest tendency to recur, mostly as sarcomas. Therefore it is thought that these lesions should be treated radically from the beginning, especially when they recur. More adequate follow-up studies are needed.

Adult↗
PubMed1975

Papillary adenomas of the colon and rectum: a twelve-year review.

During a 12-year period, 185 patients with papillary adenomas of the colon and rectum were treated. The average age was 63 years and there was a 10 per cent female preponderance. Seventy-one per cent of the lesions occurred in the rectum and rectosigmoid, and 40 per cent of the patients had rectal bleeding. Fifty-two per cent of the lesions were malignant: however, only 9 per cent of the patients died with metastatic carcinoma. The five-year survival rate in patients with papillary adenocarcinoma was 75 per cent. The results of this review indicate that a conservative approach to the surgical management of papillary adenoma of the colon and rectum should be encouraged, unless the tumor contains or is suspected to contain invasive carcinoma.

Adult↗
PubMed1970

PR objectives.

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Hospitals↗
PubMedDate not supplied

Atraumatic splenic rupture simulating ruptured sigmoid diverticulitis: report of a case and review of the literature.

A case of atraumatic rupture of the spleen originally presenting as ruptured sigmoid diverticulitis is described. The underlying disease was found to be myelofibrosis. Although progressive splenomegaly is always associated with this disease, spontaneous rupture of this organ is not reported in the literature. We also reviewed the literature in regard to unusual presentation of splenic rupture and we could not find any case simulating acute sigmoid diverticulitis. It is suggested that awareness and familiarity with this disease may enable the surgeon to suspect this diagnosis when dealing with an unusual acute abdominal emergency.

Abdomen↗
PubMedDate not supplied

Syringomyelia and scoliosis: a review of twenty-five pediatric patients.

A retrospective review of 25 patients with scoliosis secondary to syringomyelia was conducted. All patients had large syrinxes, but only 10 patients had abnormal neurologic findings, suggesting that subtle neurologic findings in patients with scoliosis should not be underestimated and supporting liberal use of magnetic resonance imaging (MRI). The results of three approaches to the care of these patients were reviewed: passive observation, bracing, and spinal fusion. Curves progressed > or = 5 degrees in patients aged < 10 years who were observed, but in children aged > 10 years, curves progressed > or = 10 degrees. Curves responded well to bracing, but correction was not maintained out of brace for patients with progressive and/or severe curves. Good corrective was achieved safely during operation.

Adolescent↗
PubMedDate not supplied

Clostridial mycotic aneurysm of the thoracoabdominal aorta--a case report.

Clostridial infection of the aorta is a rare and life-threatening condition. The management of a mycotic aneurysm involving the thoracoabdominal aorta due to Clostridium septicum infection is presented. Successful surgical management of the aortic infection involved arterial resection, wide debridement of the surrounding tissues, and in situ graft replacement. Sixteen additional cases of clostridial infection of the aortoiliac segment reported in the literature are also summarized. In ten of these 17 cases, an associated colonic adenocarcinoma was documented.

Aged↗