[Erosions and wedge-shaped defects in Swiss Army recruits].
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Adult↗
Biomedical subjects
W Bürgin
Publications and source records attributed to W Bürgin.
Computer-assisted densitometric image analysis of digital subtraction images: in vivo error of the method and effect of thresholding.
The aim of the present study was to assess the in vivo error of the method as well as the effect of thresholding when obtaining and evaluating standardized periapical radiographs for computer-assisted densitometric image analysis (CADIA). Twenty healthy volunteers participated in an experimental gingivitis study in which neither mechanical nor chemical plaque control was performed for 21 days. Two pairs of standardized periapical radiographs were taken at days 0 (baseline) and 21 (follow-up), one from a maxillary area (15 volunteers) and one from a mandibular molar/premolar area (17 volunteers). Each baseline radiograph was digitized and its image displayed on a monitor. The follow-up radiograph was then superimposed and digitized as well. After gray level correction, subtraction radiographic images were produced. The difference in gray level between the baseline and the follow-up image was calculated within each region of interest (ROI) at each picture point (pixel). In bone ROI, changes in density reflected the amount of change due to methodological errors plus the basic bone remodeling over 3 weeks. For gingival ROI, changes in density reflected the methodological error plus a possible change in soft tissue density during the experimental gingivitis. Within all of the ROI, some pixels indicated a change in gray level. A change in gray level was then thresholded; i.e., only changes >5 and then >10 gray levels were registered and used for calculation of the CADIA values. With a threshold of 5, 44/45 maxillary bone ROI and 60/66 mandibular bone ROI showed a change in density, while 41/45 maxillary gingiva ROI and 26/66 mandibular gingiva ROI indicated a change in density. With a threshold of 10, 16/45 maxillary bone ROI and 12/66 mandibular bone ROI indicated a change in density, while 13/45 maxillary gingiva ROI and 1/66 mandibular gingiva ROI indicated a change. The amounts of changes in density calculated in the various ROI were low even when applying no threshold, ranging from -0.279 to 0.621. Applying a threshold of 5, the CADIA values ranged from -0.234 to 0.727. With a threshold of 10, the changes in density ranged from -0.318 to 0.133. In vivo, CADIA of standardized radiographs indicated change in density due to methodological errors. Application of thresholds may avoid false-positive diagnoses. When applying CADIA in clinical research, the range of change to be expected due to methodological limitations as well as the threshold for true change should be evaluated. These thresholds may differ in various areas of the mouth, i.e., bone or gingival, maxillary/mandibular, anterior/posterior ROI.
Absorptiometry, Photon↗
Particulate bioglass as a grafting material in the treatment of periodontal intrabony defects.
The present clinical trial was designed to evaluate the effects of a bioactive glass, Perioglas, in the treatment of periodontal intrabony defects. 20 patients, 23-55 years of age (44 sites), with intrabony defects completed the 1-year study. Teeth with furcation involvement were excluded. After completion of initial therapy, defects were randomly assigned to either a test or control procedure. Following flap reflection, root planing and removal of chronic inflammatory tissue in both groups, the test defects were restored with the bioactive glass particulate material. Mucoperiosteal flaps were replaced, sutured and a periodontal dressing was used. All the patients received postoperative antibiotics and analgesics and were seen at 1 week for suture removal. Follow-up was then carried out weekly and at 3 months, 6 months, 9 months and 1 year post-surgery. Plaque score, bleeding score, probing pocket depth (PPD), probing attachment level (PAL) and gingival recession were recorded at baseline, 3 months and 1 year. Standardised radiographs for computer-assisted densitometric image analysis (CADIA) were taken at baseline, immediately post-operatively and at 1 year. The CADIA data showed a significant increase (F-ratio: 15.67, p < 0.001) in radiographic density and volume between the defects treated with the Perioglas when compared to those treated with surgical debridement only. PPD and PAL showed significant improvements in both experimental and control sites, with a greater trend to improvement in the experimental sites. It was concluded that this bioactive glass is effective as an adjunct to conventional surgery in the treatment of intrabony defects.
Absorptiometry, Photon↗
The effect of subcrestal placement of the polished surface of ITI implants on marginal soft and hard tissues.
In order to achieve esthetically more satisfying results, it has been proposed to place ITI implants with their border between the rough and smooth surfaces below the level of the alveolar crest, thereby obtaining a submucosally located implant shoulder following healing. The aim of the present experimental study was to clinically and radiographically evaluate the tissue response to the placement of one-stage transmucosal implants with the border between the rough and the smooth surfaces sunk by 1 mm into a subcrestal location. 11 patients underwent comprehensive dental care including the placement of 2 implants of the ITI Dental Implant System in the same quadrant (test and control). Randomly assigned control implants were placed according to the manufacturer's instructions, i.e. the border between the rough titanium plasma-sprayed and the smooth polished surfaces precisely at the alveolar crest. At the test implant the apical border of the polished surface was placed approximately 1 mm below the alveolar crest. Probing bone levels were assessed at implant placement (baseline), 4 and 12 months later. Modified plaque and modified gingival indices were recorded at 1, 2, 3, 4 and 12 months. Clinical probing depth and "attachment" levels were measured at 4 and 12 months. All parameters were assessed at 6 sites around each implant. The mean for each implant was calculated and used for analysis. The Wilcoxon matched pairs signed rank test and the Student t-test were applied to detect differences over time and between the test and control implants. At baseline, a mean difference in probing bone level of -0.86 mm (SD 0.43 mm, p < 0.05) was found between test and control implants with the test implants being placed more deeply. Both test and control implants lost a significant amount of clinical bone height during the first 4 months (test 1.16 mm, p < 0.05; control 0.58 mm, p < 0.05). However, only the test implants significantly lost clinical bone height from 4-12 months (test 1.04 mm, p < 0.05; control 0.45 mm, p = 0.08). Overall, the test implants lost 2.26 mm and the control implants 1.02 mm of bone height during the first year of service. On the average, the test implants demonstrated a bone level of 0.38 mm lower than the controls at 12 months. Except for the modified gingival index at 4 months (mean difference 0.21, SD 0.19, p < 0.05), no clinical parameters yielded significant differences between test and control implants at any time. It is concluded that in addition to the crestal bone resorption occurring at implants placed under standard conditions, the bone adjacent to the polished surface of more deeply placed ITI implants is also lost over time. From a biological point of view, the placement of the border between the rough and the smooth surfaces into a subcrestal location should not be recommended.
Adult↗
Correlations between radiographic, clinical and mobility parameters after loading of oral implants with fixed partial dentures. A 2-year longitudinal study.
The aim of present study was to correlate the changes in the peri-implant tissues occurring after functional loading of non-submerged titanium implants and assessed by radiographic, clinical and mobility measurements. 11 patients with distal extension situations received 18 implants of the ITI Dental Implant System. After a healing period of 3 months, the suprastructures were fabricated and seated 5 months post-surgically. For the assessment of peri-implant bone changes, standardized vertical bitewing radiographs with reproducible exposure geometry were evaluated using computer assisted densitometric image analyses (CADIA) and bone height measurements. Since the radiographic evaluations were performed at mesial and distal sites only, the clinical parameters from these implant aspects were included in the analysis. Clinical periodontal parameters modified for the use around implants were obtained, damping characteristics were expressed as Periotest readings and standardized radiographs were obtained at 1, 3, 6, 12 and 24 months after loading. In addition, radiographs were also taken at the start of functional loading. The data obtained from this small sample of implants demonstrated a wide range of different tissue alterations when using radiographic, clinical and mobility assessments. The parameters of probing attachment level (PAL) in combination with radiographic parameters obtained at 1, 3, and 6 months after loading were good predictors for the peri-implant tissue status at 2 years. This was shown by means of multiple stepwise regression analyses. Mobility measurements did not reveal valuable predictive information with the statistical models applied. Assessments of probing attachment levels using periodontal probes rendered information on peri-implant tissue alterations, which were closely correlated to the radiographically measurable peri-implant bone changes.
Adolescent↗
Accuracy in detecting bone lesions in vitro with conventional and subtracted direct digital imaging.
OBJECTIVE: To implement direct digital imaging (DDI) in subtraction radiography and compare the accuracy of conventional and subtracted DD images in detecting small bone lesions in vitro. METHODS: Alveolar bone defects were produced in a section of a pig mandible, with slow-speed burs 0.6, 0.7, 0.8, 0.9, 1.0, 1.2, 1.4 mm in diameter. Standardized DD images were subtracted and displayed in black and white, contrast-enhanced and pseudo-colour transformed formats. 370 pairs of slides taken directly from the computer monitor were evaluated by eight observers. RESULTS: The area P(A) under the ROC curve with DDI was 0.67 +/- 0.1. This was significantly lower (p < 0.001) than any of the three modes of subtraction radiography (mean P(A) = 0.88 +/- 0.09). The detection of small lesions (bur diameter 0.6 mm) was significantly better (p < 0.001) with contrast enhancement. Observer agreement was smaller for DDI (chi = 0.22 +/- 0.09) compared with the subtraction images (mean chi 0.64 +/- 0.13) (p < 0.001). CONCLUSION: The diagnostic characteristics of the DDI system were significantly improved by digital subtraction with image processing.
Alveolar Bone Loss↗
[Digital imaging. A report on the 3rd Symposium on Digital Imaging in Dental Radiology of 13-15 October 1994 in Noordwijkerhout, the Netherlands].
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Humans↗
[Digital imaging. A report on the 3rd Symposium on Digital Imaging in Dental Radiology of 13-15 October 1994 in Noordwijkerhout, the Netherlands].
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Radiographic Image Enhancement↗
Digital image processing. I. Evaluation of gray level correction methods in vitro.
The aims of this study were a) to assess in an in vitro model the amount of density changes measured in digitally subtracted images due to electronic noise and image alignment error, and b) to test the accuracy of different gray level correction procedures in the reduction of densitometric image mismatches. A section of a pig mandible in which a hollow cylinder ITI Bonefit implant had been placed was used to obtain pairs of standardized radiographs. Series of radiographs were obtained with different exposure times (0.34, 0.39, 0.44, 0.51, 0.58 s). The radiographs were captured through a video camera, digitized and stored in a personal computer. The same radiographic image was recorded and subtracted from itself 10 times to study the error of the method due to electronic transformations of the images and image alignment. The noise due to the analog-to-digital transformation of the radiographic images was calculated to be +/- 2 gray levels i.e., 2% of the scale of gray levels. This kind of error was reduced up to 40% by capturing the images more than once and averaging the values per pixel. The manual superimposition of the images to be subtracted caused an increase of the error to +/- 3 gray levels (2.7%). Seven methods of gray level correction based either on a linear least squares approximation or on the cumulative density function (CDF) were tested. The group based on the CDF algorithm gave significantly better results than any other method. Pixels yielding differences smaller or equal to +/- 7 gray levels (5.5% of the scale of gray levels) should be excluded from further calculations in order to eliminate (false-positive) errors due to the normalizing algorithms. Furthermore, the CDF method on an arbitrarily chosen area of the image or on the wedge seems to give to subtraction images the ability of revealing real subtle changes in tissue density (fewer false-negative errors). The use of reference structures did not futher improve the ability of the normalization methods to correct gray level mismatches between radiographic pairs.
Absorptiometry, Photon↗
Digital image processing. II. In vitro quantitative evaluation of soft and hard peri-implant tissue changes.
The aim of this study was to evaluate the ability of computer-assisted densitometric image analysis (CADIA) to detect small changes in mineralized and nonmineralized tissues adjacent to dental implants and to correlate these changes with CADIA values. A section of a pig mandible including all soft tissues and in which a hollow cylinder ITI Bonefit implant with an artificial mesial and a buccal infrabony defect was placed was used to obtain pairs of standardized radiographs. Series of radiographs were obtained with exposure times of 0.13, 0.20, 0.44, and 0.53 s. Specimens of mineralized or nonmineralized tissues were placed arbitrarily in the defects before each radiographic exposure. The radiographs were captured through a video camera, digitized and stored in a personal computer. Every radiographic image was then subtracted from a baseline one without any change. The result of the subtraction was evaluated with CADIA. A linear correlation (r2 = 0.99) was found between the bone chips (1-5 mg of dry weight) placed in the mesial defect and the CADIA values. Bone chips in the buccal defect (behind the implant), however, were not detected unless their weight reached 14 mg or more. For conventionally exposed radiographs, it was not possible to recognize soft tissue specimens (1-6 mg), either in the buccal or the mesial defect. However, when "underexposed" radiographs (exposure time: 0.13 s) were obtained, a linear correlation (r2 = 0.80) was calculated for soft tissue specimens in the mesial defect and CADIA values. In normally exposed radiographs, the CADIA system could detect even the smallest change in bone density (bone chip of 1 mg of dry bone weight) and correlated almost linearly with these changes. Provided that the radiographic images are obtained with standardized geometry and normal exposure time, the tissue density changes detected by this system within bone defects represent only mineralized tissue changes. By underexposing radiographs, CADIA may even reveal soft tissue changes around dental implants.
Absorptiometry, Photon↗
Influence of contrast enhancement and pseudocolor transformation on the diagnosis with digital subtraction images (DSI).
This study evaluated the influence of the image processing step of digital subtraction images on inter- and intraexaminer agreement in the interpretation of alveolar bone changes. 52 pairs of standardized radiographs from various clinical trials were included. Six dentists were invited to interpret the images projected as slides in random order. Display one demonstrated the slide of the digitized baseline radiograph and the follow-up image. Display two showed the regular digital subtraction image. Display three represented a grey level contrast enhanced version and displays four and five were pseudo/color enhanced subtraction images. Applying kappa-statistics and multiple regression analysis it was demonstrated that better agreements were obtained when the two color coded displays of subtraction images were shown to the interpreters. The image interpretation was performed in two series. For the first evaluation the interpreters were not informed about the therapy provided nor the time elapsed between taking the pairs of standardized radiographs. In the second series this information was provided. It could be demonstrated that the agreement in the diagnosis of bone change was less influenced by the knowledge about the clinical information if the two color-converted versions of subtracted images were evaluated. Thus, it was concluded that image processing of subtraction images using color enhancement might improve agreement in the diagnostic task. The color coded images were less influenced by the bias in the interpretation of an expected change. The decision making process might be more objective when using color enhanced subtraction images.
Alveolar Bone Loss↗
No posterior mandibular displacement in Angle Class II, division 2 malocclusion as revealed with electromyography and sirognathography.
The activity of the anterior and posterior temporal, and of the masseter muscles was studied by electromyography and the position of the mandible by sirognathography. The recordings were made in 22 children, aged 8-13 years, with Angle Class II, division 2 malocclusion before and during treatment of their malocclusion. The treatment comprised two phases: proclination of the upper incisors and bite raising with a removable plate, and the subsequent correction of the distal occlusion with an activator. The aim of the study was to reveal signs of anterior mandibular positioning during the treatment. The electromyographic recordings were made in the rest position of the mandible, and during maximal biting, chewing, and swallowing. The sirognathographic recordings comprised the positions of the mandible at rest, at intercuspation, and during tooth contact during chewing and maximal mandibular movements. The muscle activity at rest was unchanged during the period of observation. The activity during maximal biting, chewing, and swallowing decreased during the phase of proclination, which was interpreted as a result of occlusal instability. The positions of the mandible at rest, at intercuspation, and during chewing were stable during the treatment. Neither the electromyographic recordings nor the recordings of mandibular positions revealed any signs of anterior mandibular positioning during the treatment of the Class II, division 2 malocclusion.
Child↗
Remodelling of periodontal tissues adjacent to sites treated according to the principles of guided tissue regeneration (GTR).
The aim of the present study was to assess the remodelling of alveolar bone adjacent to periodontal sites following therapy according to the principles of guided tissue regeneration (GTR) using computer-assisted densitometric image analysis (CADIA), and to compare the radiographic results to traditional clinical parameters. As required for digital subtraction analyses, periodically reproducible radiographs were obtained using a modification of the Rinn System and individual acrylic bite blocks for periodical identical radiographs. Ideally, a digital subtraction image from a site where absolutely no change in density had occurred would show a perfect cancellation of the structures. An average grey level value of 128 (the middle of the digitizer grey level range set by software) would show up at each pixel. Areas with grey levels < 128 in the subtraction image would indicate loss in density and grey levels > 128 would indicate increase in density. Within the subtraction images, areas were defined using the cursor to draw "regions of interest" (ROI) projected on the bony defect exposed to GTR covering the crestal bone as well as the region of potential "bonefill". The mean, median, the standard deviation and range of the grey levels of pixels within a particular ROI were calculated. Similarly sized ROI were drawn in bone areas not exposed to the GTR procedure serving as controls. The differences in the mean grey levels of all pixels within a particular ROI between the baseline, 3 and 12 months images were calculated for documentation of gain or loss in density. From 14 patients, standardized radiographs were available from baseline, 3 months and 12 months postsurgically, depicting one infraosseous defect before and after treatment according to the principles of GTR. The densitometric changes observed in these defects were compared to the clinically assessed changes measured at the site with the deepest baseline pocket depth. A mean clinical attachment gain of 2.36 mm after 3 and 3.22 mm after 12 months was measured. This was associated with a mean reduction in the PPD amounting to 3.36 mm and 3.79 mm, respectively. The changes in the level of the FGM were rather small considering the deep original mean PPD of 7.07 mm. Over the first months, a mean recession of 1.14 mm was observed which was followed by a coronal displacement of 0.43 mm. With respect to the remodelling of the alveolar bone adjacent to the defects assessed by means of CADIA, the most pronounced changes occurred when comparing the baseline to the 12 months radiographs.(ABSTRACT TRUNCATED AT 400 WORDS)
Absorptiometry, Photon↗
Diagnosis of alveolar bone changes with digital subtraction images and conventional radiographs. An in vitro study.
The purpose of the present study was to compare the diagnostic properties of radiographs obtained with Ultra-Speed and Ektaspeed films when analyzed conventionally radiographs and after conversion in digital subtraction images. Artificial lesions, measuring 0.5, 0.7, 0.9, and 1.1 mm in diameter, were drilled in a dry skull with slow-speed burs. Standardized radiographs were obtained by means of acrylic bite blocks and a modification of the Rinn system. The results of this study demonstrated that sensitivity in the detection of the lesions was doubled after digitizing and displaying subtraction images compared with the conventional radiographic interpretation, independent of the use of Ektaspeed or Ultra-Speed films for the original radiographs. The diagnostic information seemed to be equal in radiographs obtained from Ultra-Speed and Ektaspeed films after digitization and image processing procedures.
Alveolar Bone Loss↗
Digital subtraction radiography for the assessment of changes in peri-implant bone density.
Digital subtraction radiography is proposed as a potential diagnostic tool for implant research and patient monitoring. Examples of the application of this technique are given observing peri-implant density changes during the early healing phase and during ligature-induced peri-implantitis in an animal model. Additional cases document the loss of peri-implant bone density associated with an infection and increase in density caused by remodeling after functional loading of an implant with a single crown. Digital subtraction radiography might be one of the most sensitive noninvasive methods for assessing subtle density changes in peri-implant tissues, providing additional diagnostic information on implant tissue integration and maintenance.
Alveolar Bone Loss↗
Does the mandible alter its functional position during activator treatment?
The study aimed at revealing possible changes, in activator-free periods, in the positions and movements of the mandible induced by the wearing of an activator. Twenty-one children being treated with three different types of activator for the correction of Angle Class II, Division 1 malocclusion were studied. The movement capacity of the mandible, the rest position, and the position of tooth contact during chewing were recorded with a Sirognathograph before treatment and repeatedly during the first year of treatment. With the exception of a slight increase in the maximal protrusion, no changes in mandibular movement capacity were found. The anteroposterior position of the mandible in the rest position was constant during the period of treatment, but the freeway space increased. No changes in the position of the point of tooth contact during chewing were found. The study produced no evidence of a treatment-induced forward positioning of the mandible in activator-free periods.
Activator Appliances↗
[Malocclusions in Swiss recruits in 1985].
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Adolescent↗