Search PubMed⌕ Search

Biomedical subjects

W B Webb

Publications and source records attributed to W B Webb.

At least 37 records · Page 2Linked to original sources

Mood and sleep in aging women.

The possible covariations of mood and sleep was examined in a group of 25 normal, aging women. Mood assessments made in the evenings of 3 consecutive days were independently related to both before and after sleep night. Only two sleep variables: sleep efficiency and latency to first rapid eye movement (REM) period--were reliably related to daytime moods. The relative paucity of relation between mood and sleep variables was interpreted as reflecting a general insulation of sleep from day-to-day mood variations.

Affect↗

Sleep and cognitive functions in normal older adults.

Data on cognitive and sleep variables were collected from a large, normal aging sample. The sleep and cognitive variables selected for the study had all been demonstrated previously to be sensitive to aging processes. Only two sleep variables, number of awakenings and time in Stage 1 sleep, correlated with cognitive scores. The limited number of relationships between sleep and cognitive variables was interpreted as consistent with the discontinuity hypothesis. This formulation suggests that relationships between biological and psychological measures are only present after a threshold of deterioration in the biological substrates is passed. Thus the paucity of relationships between the two variable classes is predicted in this normal aging sample.

Aged↗

A categorical approach to changes in latency, awakening, and sleep length in older subjects.

Sleep latencies, within night awakenings, and lengths of sleep of 50- to 70-year-old males and females were analyzed using a categorical procedure. Subjects were assigned to qualitatively distinct categories. The data indicate that tendencies toward sleep disturbances along these dimensions are independent but increasing across this age range. There were disproportionately large numbers of females with long latencies and males with higher amounts of awakenings.

Aged↗

Sleep apnea syndrome. A critical review of the apnea index as a diagnostic criterion.

The utility of the apnea index (number of apneic events per hour of sleep) in diagnosing sleep apnea syndrome is reviewed. Data from currently extant reports indicate that many otherwise normal, aging subjects may be classified as having sleep apnea syndrome based on the current diagnostic threshold of five apneic episodes per hour: A chi 2 analysis suggests a relationship between age and level of sleep apnea. Several other reports indicate that use of a threshold of five apneic episodes per hour does not reliably predict increased health risk or somnolence in aging subjects. Adjustment of the apnea index, based on studies of aging normal subjects and of aging patients with sleep apnea syndrome is necessary to ensure reliable results in clinical and research applications.

Adult↗

Awakenings: subjective and objective relationships.

Electroencephalographic measures of awakenings and subjective estimates of amount and frequency of awakenings were compared. The subjects were 65 men and 69 women between 50 and 70 yr. of age; their scores showed ranges on these measures. The relationships between the measures were low. Analyses of scores on the perceptual task indicate the reasons for the low relationship. The functional meaning of these findings is discussed.

Adult↗

Relationships in sleep characteristics of identical and fraternal twins.

We recorded EEGs for 14 identical and 14 fraternal young adult twin pairs during one night of sleep in our laboratory. They were instructed to sleep as long as possible. The extended sleep of the identical and fraternal twins was correlated. The structural measures of sleep of the fraternal twins were not correlated. The onset latencies, awakening measures, stage changes, and rapid eye movement amounts were significantly correlated in the identical twins. The nature of the measures used supports an interpretation of hereditary aspects of sleep length and certain structural components of sleep.

Adolescent↗

The measurement and characteristics of sleep in older persons.

Measures of the sleep structure, patterns and evaluative responses of 40 males and 40 females between the ages of 50-60 years are presented. Measurement methodology is emphasized. The inability to sustain sleep is clearly indexed by the sleep structure measures. These tendencies are greater in the males. The absolute diminution of slow wave sleep is questioned. Sleep pattern measures show wide inter and intra subject variability with few sex differences. Three fourths of the subjects reported naps in a two week period and men report more frequent but shorter naps. The subjective measures have limited concurrent relations to EEG measures and constitute a complex multifaceted content domain. The overall picture is of a system in change characterized by a wide range of individual differences.

Female↗

Sleep in older persons: sleep structures of 50- to 60-year-old men and women.

Electroencephalographically measured sleep of 80 healthy men and women between the ages of 50 and 60 years was measured for three nights. Compared with the sleep of a younger group of men and women (20 to 30 years), their sleep was characterized by more frequent and prolonged awakenings and shorter sleep stage periods. Older men displayed greater age-related changes than older women. There was an increase in the reliability of measures in the older persons across nights. When a modified scoring procedure for slow wave sleep based on frequency alone was used, the typically reported age decline was not found.

Aging↗

The REM cycle, combining rules, and age.

Standardized scoring of the EEG records of older subjects (50 years or older) revealed frequent brief interruptions of the REM periods. In the absence of rules that would permit incorporation of these transient interruptions, there is a marked increase in the number of REM episodes and a significant change in average period length and REM cycle measures. This paper explores the use of rules that combined the interruptions of different lengths (5 min and 15 min) in the ongoing REM period. Populations of 40 males and 40 females who were 50-60 years old were compared with samples of 15 males and 15 females between 19 and 31 years of age. The use of combining rules had little effect on the younger samples and a limited effect on the older females. For the males the use of combining rules reduced the number of periods by one-half and doubled the average REM period length and the REM cycle. While these measures approximate the normative figures of the other samples, they remain significantly different from them. Scoring of all records by a 5-min combining rule is recommended, as is also the use of no-rule scoring as a measure of REM period stability.

Adult↗

Sleep stage responses of older and younger subjects after sleep deprivation.

EEG sleep stage measures were obtained on younger subjects (18-22 years) and older subjects (40-50 years) at 9 a.m. after 2 nights of sleep loss. The first 200 min were compared. Both groups displayed sharply reduced latencies and increased stage 4 sleep. The proportionate distribution of stage amounts and numbers was not different. However, the younger group entered slow wave sleep more quickly.

Adolescent↗