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Biomedical subjects

W Ax

Publications and source records attributed to W Ax.

At least 37 records · Page 2Linked to original sources
PubMed1978

[Diagnosis of malignant processes of the colon and rectum using a new method for the demonstration of sensitized lymphocytes (PAL-test)].

Peripheral blood lymphocytes of 45 patients with colon-rectum disease and 30 healthy controls were tested in a simple rapid microagglutination test (PAL test) for cancer diagnosis. In 30 cancer patients 28 positive reactions were obtained. All healthy controls were negative. The 15 patients with benign or premalignant lesions showed 5 positive and 10 negative reactions. Results of the PAL test were about 90% accurate.

Agglutination Tests↗
PubMed1977

Detection of sensitized human blood lymphocytes by agglutination with basic peptides: a possible test for malignant disease.

A simple rapid micro-agglutination test for detecting sensitized lymphocytes from human peripheral blood is described: the poly-L-lysine (PLL) 3400 agglutination test of lymphocytes (PAL test). The incubation of lymphocytes from 30 cancer patients, 30 patients with non-malignant disease and 40 healthy controls with PLL (mol. wt 3400) is evaluated. The test was positive in 83 percent of malignant and 20 percent of non-malignant cases. All healthy controls were negative. Other peptides tested showed no significant difference in reaction between malignant and non-malignant diseases. The mechanism of detection of sensitized lymphocytes from patients with malignant disease through agglutination induced by PLL 3400 is discussed.

Agglutination Tests↗
PubMed1975

Cell-mediated immunity in patients with renal adenocarcinoma.

The lymphocytotoxicity test was used to study the existence of immunologically active lymphocyte reactions in patients with renal carcinoma at different stages. In 9 patients with an advanced renal carcioma (stage IV) a low lymphocytotoxicity was found, while the examination of 7 patients with stage I and II renal tumours showed a high value of the lymphocytotoxicity test. The clinical importance of the lymphocytotoxicity test is discussed with special interest in a possible immunotherapy.

Adenocarcinoma↗