[High pressure headache and internal neurologic disease].
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Headache↗
Biomedical subjects
W Autenrieth
Publications and source records attributed to W Autenrieth.
[Migraine and other primary headaches].
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Headache↗
[Cerebrospinal fluid passage of therapeutic immunoglobulins of the IgG class in infectious inflammatory disease of the CNS].
Immunoglobulins are often used as an optimizing therapy in cases of infectious diseases of the central nervous system. To clarify the question of whether or not an intravenously administered compound of the IgG class is able to penetrate the cerebrospinal fluid barrier despite its high molecular weight, 12 anti-HBs negative patients received 20 ml each of a beta-Propiolacton treated IgG compound with a high anti-HBs titre (1 : 115 000) used as a marker. Four patients having an inconspicuous fluid condition were consulted for control. Five patients were suffering from slight disturbances and three other patients had severe disorders of the blood-cerebrospinal fluid barrier function resulting from inflammatory diseases of the central nervous systems. Cerebrospinal fluid was produced by way of lumbar puncture resp. drainage for the determination of anti-HBs. Simultaneously, the concentration of antibodies in serum was determined. In all patients having barrier disturbances, anti-HBs was evident in the cerebrospinal fluid, the transfer of intravenously administered immunoglobulins to cerebrospinal fluid increasing in correlation with the degree of the barrier disorder. The therapeutical importance of immunoglobulin therapy in treating infections of the central nervous system is pointed out.
Adult↗
[Side effects of long-term drug therapy in neurology (author's transl)].
In default of a causal treatment, longterm drug therapy is essential in numerous neurological diseases. For forensic reasons alone, therefore, side effects and interactions typical for the drugs must be taken into consideration. An attempt has been made to review the most important disturbances of longterm treatment with the drugs which are often used in neurology. At the same time the versatile chemotherapeutic substances also used in other special disciplines and which can sometimes produce serious neurological symptoms are also discussed.
Adrenal Cortex Hormones↗
[Early symptoms and diagnosis of multiple sclerosis].
Multiple Sclerosis is one of the most common neurological diseases in North and Central Europe and USA, the prevalence is 0,03-0,06%. The precise aetiological and pathological processes underlying the disease are still unknown. As there is as yet no laboratory test that is specific for Multiple Sclerosis, the diagnosis is still a clinical one. It depends on the history--a majority of patients has a history of remissions--and on the demonstration of objective signs of lesions in the white matter of the central nervous system. There can be found some early symptoms--such as optic neuritis--and some typical combinations of symptoms that make the diagnosis Multiple Sclerosis probable or clinically definit. Among the laboratory tests the investigation of cerebrospinal fluid is most important.
Adult↗