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Biomedical subjects

W Abramovits

Publications and source records attributed to W Abramovits.

18 recordsLinked to original sources
PubMed2001

Cyclosporine and tacrolimus in dermatology.

Immune modulators are being used with increasing frequency in dermatology. This article reviews two such agents, cyclosporine and tacrolimus. Discussion emphasizes the pharmacology, side effects, and uses of these two drugs in dermatologic disorders.

Cyclosporine↗
PubMed2000

Sebum, cosmetics, and skin care.

Recent contributions to the understanding of the physiology and biochemistry of sebum production and of the lipids on the skin surface are leading to the development of effective strategies to regulate excessive sebum production and its consequences through the use of cosmetics and skin care products.

Acne Vulgaris↗
PubMed1996

Ultrasound-guided thermocouple placement for cryosurgery.

BACKGROUND: Although cryosurgical methods have high cure rates, imprecise estimates of both skin lesion depth and destructive temperature front location result in subjective technique in skin malignancy treatments. OBJECTIVE: We evaluated the possibility of newer ultrasound equipment to assist in the precise placement of thermocouples in human skin. METHODS: DermaScan C ver. 3 ultrasonographic equipment fitted with a sharp focus probe with a frequency of 20 MHz and a scan length of 12.1 mm was used to locate thermocouples with 27- and 30-gauge needles. RESULTS: We successfully and reproducibly located thermocouples and thin needles, and accurately measured their distance from the skin surface. CONCLUSION: Ultrasound is a useful method for the accurate placement of thermocouples, and needles as thin as 30 gauge for monitoring in cryosurgery.

Cryosurgery↗
PubMed1993

Multiple agminated pigmented Spitz nevi (mimicking acral lentiginous malignant melanoma and dysplastic nevus) in an African-American girl.

BACKGROUND: Reed's nevi are distinguished from Sptiz tumors by their significant melanogenesis and growth pattern. They may be confused with melanoma on clinical and histologic grounds. CASE REPORT: An unusual case in which multiple agminated Reed's nevi mimicked acral lentiginous malignant melanoma in an African-American girl is presented. A critical review of the literature is presented to assist in the diagnosis. CONCLUSIONS: Awareness of this entity and of its possible clinical presentations and judicious application of conventional hematoxylin-eosin microscopic criteria remain the most useful methods to bring the correct diagnosis in most instances. Mutilating or excessive surgery may be avoided for most cases of pigmented spindle and epithelioid cell nevus.

Black People↗
PubMed1991

Autosomal recessive ectodermal dysplasia: I. An undescribed dysplasia/malformation syndrome.

We describe 27 individuals of 7 families related to each other with high probability who showed manifestations of ectodermal dysplasia and other anomalies affecting females as severely as males with variable expressivity. All parents were normal. These families were detected in a relatively isolated and inbred population with very small neighbouring communities from a Caribbean Sea island, Margarita Island, in Northeastern Venezuela (Nueva Esparta State). The clinical picture common to all patients could not be classified within the heterogeneous group of known ectodermal dysplasias and the published cases do not resemble our patients. We believe that this condition constitutes a newly recognized autosomal recessive dysplasia/malformation syndrome of ectodermal dysplasia.

Adolescent↗
PubMed1985

Dermatofibrosarcoma non-protuberans: description and report of five cases of a morpheaform variant of dermatofibrosarcoma.

Five cases of dermatofibrosarcoma are reported. All showed features typical of dermatofibrosarcoma protuberans except that in four cases, and a portion of the fifth case, no protusion of the tumor was noted clinically despite the rather advanced stage of growth of the tumor. These lesions resembled morphea or a morpheaform basal cell carcinoma clinically but could be recognized as "dermatofibrosarcoma non-protuberans" by physicians who had observed a previous case.

Adolescent↗
PubMed1982

Coexistence of lichen planus and systemic lupus erythematosus.

Three cases of the simultaneous occurrence of lichen planus (LP) and systemic lupus erythematosus (SLE) are presented. Each patient had clinical, histologic, and immunopathologic LP. Additionally, each patient had clinical SLE that fulfilled the American Rheumatism Association criteria for the diagnosis of SLE. The clinical manifestations of SLE were predominantly cutaneous. The three patients had positive lupus band test and high titers of antinuclear antibodies. One patient had vitiligo in addition to SLE and LP. LP and SLE have common clinical, histologic, and immunopathologic features. It is possible that a common agent (or agents) may cause either disease or the overlap syndrome, depending on the immunogenetic predisposition of the patient.

Adult↗
PubMed1980

Trichotillomania in adults.

The cause of hair plucking is purely psychological. The extent of the hair plucking and the area from which the hair is plucked seem to have no direct correlation with the patient's underlying psychopathologic behavior. Hair plucking that begins in childhood and extends into adolescence and adulthood may represent a more complex psychopathologic condition. Therapy can consist of confronting the patient with his behavior and helping him cope with the triggering stressful external causes. Psychiatric consultation is suggested if this is not helpful. Trichotillomania by definition implies psychosis. Since this behavior is seldom associated with psychosis, we suggest the term hair plucking be used to describe this syndrome. Herein, we present two cases of trichotillomania (hair plucking), review of the relevant literature dealing with the psychopathologic nature of this disorder, and suggest methods for managing these patients.

Adult↗
PubMed1980

A report of two patients with lichen aureus.

Two patients with lichen aureus are described. The clinical and histologic features of our patients were compared with previously reported cases of lichen aureus in an effort to classify this entity properly among the pigmented purpuric dermatoses. We regard lichen aureus as a distinct entity. Although this disorder has been described principally in adult patients it began at the age of 14 years in one of our patients.

Adult↗
PubMed1978

A zinc-deficiency dermatitis in patients on total parenteral nutrition.

Three patients on home total parenteral nutrition utilizing a synthetic amino acid solutions developed a dermatitis consistent with acrodermatitis enteropathica after 30, 43 and 62 days of therapy. The dermatitis resolved after changing to casein hydrolysate in 2 patients and after full oral alimentation in the third. Although measured serum zinc levels were repeatedly normal to elevated in all patients, sufficient retrospective data analysis combined with literature review on this subject, clearly implicates zinc deficiency as the etiology for their dermatitis. Adequate zinc supplementation of synthetic amino acid solutions is essential in order to avoid this complication.

Adolescent↗