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Biomedical subjects

W A Miller

Publications and source records attributed to W A Miller.

At least 163 records · Page 9Linked to original sources

Endotoxin: stimulation of bone resorption in tissue culture.

Bacterial endotoxins can stimulate the release of previously incorporated calcium-45 and tritiated proline from fetal rat bone in tissue culture. Endotoxin from Bacteroides melaninogenicus, an organism regularly found in the gingival crevice of man, produces a response similar to parathyroid hormone and is effective at doses as low as 0.1 microgram per milliliter. This response is inhibited by serum and dependent upon the presence of albumin. Endotoxins may play a role in the bone loss characteristic of human periodontal disease.

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