Biomedical subjects

W A Hubbard

Publications and source records attributed to W A Hubbard.

3 recordsLinked to original sources

PubMed1992

Diabetes in an elderly population. A controlled study of morbidity and outcomes.

OBJECTIVE: To determine in an elderly diabetic population the frequency of vascular and related disorders, the mortality, and outcomes compared with a matched control group. SETTING: The Queen Elizabeth Geriatric Centre, Ballarat, Victoria. METHOD: The medical records of all diabetics admitted between 1982 and 1987 inclusive, and a control group matched for age, sex and ward of admission were studied retrospectively. The presence of associated conditions and outcome parameters were entered in to a database and analysed statistically. RESULTS: Increased prevalence in individuals with diabetes of ischaemic heart disease (2.0:1.0), cerebrovascualr accident (1.9:1.0) and hypertension (1.5:1.0). Similar death rate, cumulative bed days, discharge destination and use of discharge services. CONCLUSION: Despite the more frequent presence of clinical vascular disease, an elderly population with diabetes had the same outcomes as matched controls and did not require more bed occupancy or use of community based services.

Aged↗

PubMed1983

Comparison of the B-D urine culture kit with a standard culture method and with the MS-2.

A total of 100 random clinical urine specimens were divided and used to compare Becton, Dickinson & Co. B-D Urine Culture Kit-treated urine (BDU) with refrigerated urine (RU). Each RU-BDU pair was cultured with the standard calibrated loop-plate method and also screened with the Abbott Laboratories MS-2 system at 0, 5, and 24 h. An additional 158 positive urine specimens containing greater than 10(5) CFU/ml were tested by standard culturing and MS-2 at 0 and 24 h. In addition, growth curves were run for Escherichia coli containing RU-BDU pairs at 0 and 24 h, and MS-2 detection time frequencies were analyzed. Culture results showed few changes in colony counts at 0 and 5 h for RU and BDU specimens. At 24 h, there were decreased colony counts for 7.0% of RU and 17.7% of BDU specimens. MS-2 results showed detection rates at 0 h of 100% for RU and 82.9% for BDU specimens and at 24 h of 91.1% for RU and 63.3% for BDU specimens. The organisms most frequently missed at 24 h were E. coli, Pseudomonas aeruginosa, and Staphylococcus epidermidis. Growth curve analysis showed a 1-h delay of logarithmic growth in BDU specimens. MS-2 detection time analysis showed delayed positive reports owing to be extended detection time for BDU specimens. The B-D Urine Culture Kit is a convenient transport system; however, some difficulty in recovering organisms at 24 h with the standard culture method and increased difficulty with the MS-2 system were recognized.

Bacteriological Techniques↗

PubMed1976

Intraocular pressure decrease in normal volunteers following timolol ophthalmic solution.

Timolol ophthalmic solutions 0.5 per cent, 1.0 per cent, and 1.5 per cent lowered intraocular pressures significantly in normal human volunteers. Maximum lowering of the intraocular pressures was reached at two hours with the 0.5 per cent solution of timolol and at one hour with the 1.0 per cent and 1.5 per cent timolol ophthalmic solutions. The effect lasted the full seven hours of observations. No objective or subjective evidence of ocular irritation could be attributed to the drug. A single dose of timolol applied topically to the eyes of normal human volunteers had no effect on pupillary size, visual acuity, blood pressure, or pulse rate.

Adrenergic beta-Antagonists↗