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Biomedical subjects

W A Fuchs

Publications and source records attributed to W A Fuchs.

At least 109 records · Page 6Linked to original sources

Arteriography in bone tumours.

The usefulness of arteriography in the diagnosis and management of bone tumours has been evaluated in 78 cases (49 malignant neoplasms, 17 benign tumours and 12 inflammatory lesions). Using well-defined criteria, of which the presence or absence of tumour vessels is of decisive importance, arteriography represents - not as a routine procedure but in selected cases - a most useful guide to establishing the diagnosis, by adding important information to standard radiography, by defining the extent of the lesion and by assisting in the selection of the best site for biopsy.

Adolescent↗

[Radiological diagnosis of closed trauma to the aorta (author's transl)].

Closed injury to the thoracic aorta at the isthmus occurred after street accidents in eight persons (five males, three females, aged 17-55 years). The lesions ranged from isolated intimal rupture to complete loss of continuity of the aorta. Radiological diagnosis or thoracic surgical exploration took place in five patients within 48 hours of the accident, while in the remaining three--alle with a false aneurysm of the thoracic aorta-the time elapsed before accurate diagnosis ranged from three months to seven years. Five patients were successfully operated upon. It is stressed that successful surgical intervention depends on early and accurate radiological diagnosis (chest X-ray and, if necessary, aortogram).

Accidents, Traffic↗

[Slow infusion cholangiography in patients with jaundice].

Thirty patients with jaundice and serum bilirubins above 4 mg.% were examined by slow infusion cholangiography (40 ml. (20 g.) Ioglycamid in 500 ml. 0.9% NaC1 in ten hours). Diagnostic results were achieved in 38%; in 15 patients with extra-hepatic obstruction, the success rate was 13%, whereas in disease of the liver parenchyma, the success rate was 60%.

Adult↗

Lymphography as a guide to prognosis in malignant testicular tumours.

Lymphography was performed in 130 patients with malignant neoplasm of the testes. The patients were treated by irradiation, supplemented by chemotherapy when lymph node metastases were present. The survival rates of the various pathologic subdivisions were analyzed according to the lymphography. The following 5-year survival rates were observed: seminoma: normal lymphography 94%, pathologic lymphography 69%; teratocarcinoma: normal lymphography 86%, pathologic lymphography 14%; embryonal carcinoma: normal lymphography 64%, pathologic lymphography 33%.

Adolescent↗

Lymphography in carcinoma of the uterine cervix.

Lymphography was carried out in a series of 158 patients with carcinoma of the uterine cervix. The diagnostic accuracy rate of 85 per cent compares favourably with the results of a similar investigation made ten years ago. Positive lymphography does not alter the survival rate in clinical stages I and II, probably due to the more accurate and selective therapeutic approach induced by lymphography. In stage III the 2-year survival rate of patients with negative findings is 58 per cent compared to only 17 per cent in case of positive lymphographic findings.

Adult↗

Prolonged drip-infusion cholangiography.

Previous experimenttal work in animals has shown that the hpatic excretion of iodipamide and ioglycamide is subject to a transport maximum (TM). Doses in excess of this TM are largely excreted in the urine. In the present study the TM for man was estimated in three subjects with indwelling T-tubes: figures of 19-23 mg/minute for ioglycamide were obtained. It was thought that prolonged administration of contrast at levels slightly above the TM might have advantages in patients with impaired liver function. In obstruction the gradual excretion of contrast could improve the chances of filling the ducts completely, while in hepato-cellular disease the gall bladder might have time to concentrate the contrast. Ioglycamide was therefore given by slow overnight infusion, equivalent to 35 mg/minute, to patients in whom standard cholangiography had been unsuccessful. The overall success rate was 75 per cent with similar improvement in obstructive and hepatocellular disease.

Adult↗