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Biomedical subjects

W A Beresford

Publications and source records attributed to W A Beresford.

At least 19 recordsLinked to original sources
PubMed1996

Enlivening basic-science learning with current journal articles.

Pre-clinical medical students are often unconvinced that the basic sciences are clinically valuable. Also, they are hesitant about formulating ideas on their own from non-textbook sources. First-year medical students taking histology or neurobiology were persuaded to consult articles from the current biomedical literature. I set brief short-answer and labeled-sketch questions well before the course theoretical examinations, where the answers counted toward the score. The answers could only be found by reading in articles made available in the laboratory. The articles were chosen to display basic-science knowledge in action in clinical contexts. The questions offer an additional curriculum that can be steered toward, for example, concerns of family practice, mechanisms of common diseases, and topics of fast-increasing clinical importance.

Biological Science Disciplines↗
PubMed1993

Fibrous trabeculae in the liver of alligator (alligator mississippiensis).

In the mature alligator, fibrous trabeculae run from the portal areas and capsule through the hepatic parenchyma. The extent of these trabeculae becomes clear only after staining for collagen with, for example, Fast green or Picrosirius red. The trabeculae are less well developed in young caiman. The alligator's liver might use the trabeculae to withstand thrashing of the body.

Alligators and Crocodiles↗
PubMed1984

Ectopic decidual cell reaction in para-aortic and pelvic lymph nodes in the presence of cervical squamous cell carcinoma during pregnancy.

Bilateral para-aortic lymphadenectomy is routine prior to radical surgery in cancer of the cervix. A pregnant patient with invasive cancer of the cervix and ectopic decidual cell reaction in para-aortic and pelvic nodes is presented. A decidual cell reaction in frozen sections of para-aortic lymph nodes could be confused with metastatic disease. Pathogenesis of ectopic decidual cell reaction is discussed.

Adult↗
PubMed1979

The aging intervertebral disk.

This paper outlines the structure of the intervertebral disk and the process by which altered cellular mechanisms lead to deterioration with age. A reference list indicates current trends in research that attempt to explain the changing nature of the intervertebral disk and its role in spinal disease.

Aging↗
PubMed1977

The penile bone and anterior process of the rat in scanning electron microscopy.

The penile bone and anterior process were made anorganic for scanning electron microscopy. The mature bone has a basal bulb and a long, cylindrical shaft bevelled at its tip to fit under a matching surface on the anterior process, giving rise to a bevelled 'suture'. A rough, resting, Sharpey-fibre bone surface covers the base and tip of the bone, the dorsal crest along the shaft, and parts of the lateral and ventral surfaces. The penile bone grows by endochondrial ossification at its basal end, but the cartilage cells are randomly disposed and not arranged in columns as in most 'long' bones. The growing bone, at 8 weeks, shows evidence of resorption externally where the base 'waists in' to the shaft: the corresponding endosteal surface within the basal bulb is formative, in accordance with the 'V-principle' of remodelling. It is concluded that the anterior process, penile bone and proximal erectile body (corpus cavernosum) form a firm, tightly fastened, articulating chain, perhaps serving to aid penetration.

Aging↗
PubMed1977

Intracerebral transplantation of the genital tubercle in the rat: the fate of the penile bone and cartilages.

Genital tubercles of 70 newborn male and female rats were transplated into the brains of unrelated infant rats. Seven other tubercles were placed subcutaneously. All female, and some male, hosts were injected with testosterone propionate. After surviving from 2-24 days,, histological study of 49 successful grafts showed survival of the urethral and balano-preputial epithelia and growth of the preputial glands, which formed secretion-filled cysts and became the major component of the graft. The fate of the mesodermal tissues witin the glands varied between remaining in an undeveloped state, with only pale fibrouw tissue and an area of granular degeneration and giant cells, and achieving an incompletely differentiatel state in which erectile tissue and the anterior process of fibrocartilage had formed and the glans had grown but the penile bone and its secondary growth cartilage failed to appear. Grafts could reach this degree of differentiation of the glands irrespective of transplantation site, attachment to the host dura, the sex of donor or host, and whether or not male hosts were given exogenous hormone.

Animals↗