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Vincent Y W Lee

Publications and source records attributed to Vincent Y W Lee.

At least 19 recordsLinked to original sources

Comparison of outcomes of primary scleral-fixated versus primary anterior chamber intraocular lens implantation in complicated cataract surgeries.

OBJECTIVE: To compare the visual outcomes and complication profiles of primary scleral-fixated intraocular lens (SFIOL) versus primary anterior chamber intraocular lens (ACIOL) implantation in cataract surgeries complicated by inadequate capsular support. DESIGN: Retrospective, interventional, comparative cases series. PARTICIPANTS: Thirty-six eyes of 36 patients undergoing SFIOL implantation (group 1) and 46 eyes of 46 patients undergoing ACIOL implantation (group 2). METHODS: Retrospective analysis of medical records of a consecutive series of complicated cataract surgeries with primary SFIOL or ACIOL implantation. MAIN OUTCOME MEASURES: Postoperative best-corrected visual acuity (BCVA), intraoperative and postoperative complications, if any, and postoperative corneal endothelial cell counts. A multiple linear regression model was constructed with postoperative BCVA as the dependent variable and with IOL group (SFIOL vs. ACIOL), preoperative BCVA, surgeon's operative experience, planned operation, and patient's age as independent variables. RESULTS: Fifty-eight percent (group 1) and 37% (group 2) of patients underwent phacoemulsification, whereas the rest underwent extracapsular cataract extraction. The mean postoperative follow-up was 33.4+/-17.9 months (range, 6-61 months). Postoperative Snellen BCVA of 20/40 or better was achieved in 47.2% (group 1) and 71.7% (group 2) of patients (P = 0.038). Regression analysis showed that primary ACIOL implantation was associated with a significantly better postoperative BCVA of -0.157 on the logarithm of minimum angle of resolution scale (95% confidence interval, -0.306 to -0.007; P = 0.040), compared with primary SFIOL implantation. Although both the number of eyes with complications and the total number of complications were higher in the SFIOL group, the differences in early (P = 0.073) and late (P = 0.377) complications were not statistically significant. CONCLUSIONS: The results indicate that satisfactory results are achieved with primary implantation of current open-loop ACIOLs during cataract surgery complicated by loss of posterior capsule integrity. Eyes with these IOLs fared better than a cohort of eyes undergoing SFIOL implantation in a similar situation, at intermediate-term follow-up. Further prospective clinical trials with longer follow-up may help to evaluate the long-term visual outcomes and complication profiles after primary implantation of these lenses.

Aged↗

Effect of application duration of 2% lidocaine jelly on aqueous lidocaine concentration for topical anesthesia in cataract surgery.

BACKGROUND: To evaluate the intraocular penetration of lidocaine 2% gel after different duration of application and to assess their effects on intraoperative pain. METHODS: Samples of aqueous humor were obtained in 41 eyes that had phacoemulsification under topical anesthesia with 2% lidocaine gel. The duration between lidocaine gel application and paracentesis was recorded. The aqueous concentration of lidocaine was measured using high performance liquid chromatography (HPLC). Patients were also asked to report the severity of intraoperative pain using a verbal analogue scale. Correlation analysis was performed to analyze the relationship between duration of lidocaine gel application, aqueous lidocaine concentration and intraoperative pain score. RESULTS: The mean duration of lidocaine gel application was 20.3+/-6.1 min and the mean aqueous lidocaine level was 14.2+/-8.5 micro g/ml. Longer duration of lidocaine gel application was significantly associated with higher aqueous concentration of lidocaine (Spearman's rho=0.58, P<0.001). Eyes in which lidocaine gel was applied for 20 minutes or more had significantly higher aqueous lidocaine level (two-tailed t-test, P=0.001) However, the duration of lidocaine gel application and the aqueous concentration of lidocaine showed no correlation with the patent's perceived pain score (P=0.20 and P=0.79, respectively). CONCLUSIONS: Increase in duration of lidocaine gel application resulted in higher aqueous concentration of lidocaine. Patients' level of perceived pain during phacoemulsification under lidocaine gel anesthesia was not related to the intraocular lidocaine absorption level after 10 min of gel application.

Adult↗

Visual experiences during vitreous surgery under regional anesthesia: a multicenter study.

PURPOSE: To investigate patients' subjective intraoperative visual experiences during vitreous surgery performed under regional anesthesia, to ascertain if patients were frightened by their visual experiences, and to determine the risk factors associated with a frightening visual experience. DESIGN: Multicenter, prospective study. METHODS: Sixty-five patients who had vitreous surgery under regional (retrobulbar or peribulbar) anesthesia in five centers in Ireland, Singapore, and Hong Kong were interviewed within 2 hours of their operation using a standardized questionnaire. RESULTS: Thirty patients (46.2%) perceived light perception throughout the entire operation, 19 patients (29.2%) experienced transient loss of light perception, and 16 patients (24.6%) experienced no light perception throughout the entire duration of the surgery. Nine patients (13.8%) were frightened by their intraoperative visual experiences. Patients who were frightened by their visual experiences were more likely to see color (100%) than those who were not frightened (55.4%) (P = .010). The mean age of the patients who were frightened was lower (51.8 years) compared with those who were not frightened (64.6 years) (P = .003). The mean duration of surgery was longer for patients who were frightened (118.9 minutes) compared with those who were not frightened (91.2 minutes) (P = .047). CONCLUSIONS: Most patients undergoing vitreous surgery under regional anesthesia retained at least light perception intraoperatively. Importantly, 13.8% of patients were frightened by their visual experiences. A younger age, longer duration of surgery, and perception of color were risk factors for a frightening visual experience.

Adult↗