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Vikram Patel

Publications and source records attributed to Vikram Patel.

At least 37 records · Page 2Linked to original sources
PubMed2005

The impact and patterns of hazardous drinking amongst male industrial workers in Goa, India.

AIMS: The aim of this study was to describe the impact and patterns of drinking in hazardous drinkers in a male industrial worker population in India. METHOD: A case-control design was used, and 234 subjects (75 hazardous drinkers, 78 casual drinkers and 81 abstinent workers) were randomly selected from a population of male workers who had participated in a survey of drinking behaviour. The definition of these categories was based on the scores of subjects on the Alcohol Use Disorders Identification Test (AUDIT). Subjects were interviewed with a semi-structured social and health impact questionnaire, Revised Clinical Interview Schedule (CISR) and Brief Disability Questionnaire (BDQ). A total of 184 spouses of consenting workers were also interviewed with a semi-structured interview, the CISR,BDQ and AUDIT. A sub-group of 55 hazardous drinkers participated in a descriptive study of patterns of drinking, recording drinking behaviour using a daily drink diary over a 1-month period. FINDINGS: Hazardous drinkers have significantly poorer physical and mental health and show trends for adverse social outcomes such as violence. Casual drinkers, on the other hand, were no different from abstinent subjects on any of the key outcomes. As compared to casual drinkers, hazardous drinkers tend to drink alone, in bars, and prefer non-commercial alcoholic beverages which are cheaper and have high alcohol concentration. CONCLUSIONS: Hazardous drinking has a significant adverse impact on drinkers and their families. Hazardous drinkers display unique drinking patterns suggesting the role of stigma and preference for higher alcohol-containing, but cheaper, drinks available in India.

Adult↗
PubMed2005

Poverty, violence and depression during pregnancy: a survey of mothers attending a public hospital in Brazil.

BACKGROUND: Depression in women is associated with social deprivation and violence. We describe the prevalence and risk factors for depression during pregnancy, in particular the association with poverty and violence, in a Brazilian setting. METHOD: A cross-sectional survey of women in the third trimester of pregnancy attending a public hospital maternity clinic from August 2003 to July 2004 in Rio de Janeiro. Participants were interviewed about their sociodemographic status, obstetric and medical conditions, substance use, stressful life events, and social support. Depression was diagnosed through the Composite International Diagnostic Interview (CIDI). RESULTS: A total of 230 of 240 eligible women consented to participate. The 12-month prevalence of depression was 19.1% (95% CI 14.4-24.9). On multivariate analyses, having been educated beyond primary school was protective (OR 0.5, 95% CI 0.2-0.9). Risk factors were: being divorced or widowed (OR 4.9, 95% CI 1.3-18.3); a history of depression before pregnancy (OR 7.9, 95% CI 3.1-20.5); loss of an intimate relationship (OR 8.4, 95% CI 3.3-21.4), experienced financial difficulties (OR 6.6, 95% CI 2.5-17.2) and having been exposed to violence in the previous year (OR 4.2, 95% CI 1.5-11.8). CONCLUSIONS: Depression is common during pregnancy and is associated with indicators of socio-economic deprivation, violence and the loss of an intimate relationship, and with a previous history of depression. Psychosocial interventions and appropriate social policies need to be implemented in this population to reduce the burden of maternal depression.

Adolescent↗
PubMed2005

Integrating mental health in global initiatives for HIV/AIDS.

A more prominent role is needed for mental health interventions in global HIV/AIDS initiatives -- such as the World Health Organization'3 by 5' Initiative. Significant numbers of infected people have, or develop, mental health problems, and this often adversely impacts on HIV/AIDS treatment and adherence. Integrating psychiatric and psychosocial interventions should benefit both the mental and the physical health of people living with HIV/AIDS.

Delivery of Health Care, Integrated↗
PubMed2005

Validity of the construct of post-traumatic stress disorder in a low-income country: interview study of women in Gujarat, India.

The validity of the clinical construct of post-traumatic stress disorder (PTSD) has been questioned in non-Western cultures. This report describes in-depth interviews exploring the experiences of women who were traumatised by the communal riots in Ahmedabad, India, in March 2002. Three specific narratives are presented which describe experiences that closely resemble re-experiencing, avoidance and hyperarousal. Thus, symptoms described as characteristic features of PTSD in biomedical classifications are clearly expressed by the women in our study, and are attributed by them to trauma and grief. We conclude that PTSD may be a relevant clinical construct in the Indian context.

Adult↗
PubMed2004

Under-representation of developing countries in the research literature: ethical issues arising from a survey of five leading medical journals.

BACKGROUND: It is widely acknowledged that there is a global divide on health care and health research known as the 10/90 divide. METHODS: A retrospective survey of articles published in the BMJ, Lancet, NEJM, Annals of Internal Medicine & JAMA in a calendar year to examine the contribution of the developing world to medical literature. We categorized countries into four regions: UK, USA, Other Euro-American countries (OEAC) and (RoW). OEAC were European countries other than the UK but including Australia, New Zealand and Canada. RoW comprised all other countries. RESULTS: The average contribution of the RoW to the research literature in the five journals was 6.5%. In the two British journals 7.6% of the articles were from the RoW; in the three American journals 4.8% of articles were from RoW. The highest proportion of papers from the RoW was in the Lancet (12%). An analysis of the authorship of 151 articles from RoW showed that 104 (68.9%) involved authorship with developed countries in Europe or North America. There were 15 original papers in these journals with data from RoW but without any authors from RoW. CONCLUSIONS: There is a marked under-representation of countries in high-impact general medical journals. The ethical implications of this inequity and ways of reducing it are discussed.

Africa↗
PubMed2004

Are visual measures of mood superior to questionnaire measures in non-Western settings?

OBJECTIVE: We hypothesised that, in a non-Western setting where literacy was not universal, a visual measure (the FACES test) would be more valid than a traditional psychiatric questionnaire [the General Health Questionnaire (GHQ)] as a screening test for mood disorders. METHODS: The study was nested within a randomised controlled trial of 450 patients with a common mental disorder (CMD). Subjects were evaluated at 2, 6 and 12 months after enrolment with the Clinical Interview Standardised-Revised (CISR) (the gold standard), the GHQ5 (the shortened version of the GHQ-12) and the FACES test. RESULTS: Correlation coefficients and Receiver Operating Characteristic (ROC) curves show superiority of the GHQ5 in the detection of CMD based on the CISR, compared with the visual FACES test. Less-educated subjects had particular difficulty completing the FACES. The kappa coefficient of agreement between the two instruments, using the cut-off point for the GHQ5 estimated by the ROC curves, was between 0.70 and 0.75. CONCLUSIONS: Contrary to our hypothesis, the questionnaire-based measure was significantly superior to a visual measure of mood, especially for less-educated subjects. A short five-item version of the GHQ has a good discriminatory ability for CMD and may be used as a brief alternative to standardised interviews in clinical and survey settings.

Adolescent↗
PubMed2004

The accuracy of high-resolution ultrasound for evaluating focal lesions of the hand and wrist.

PURPOSE: Although several articles have described the sonographic features of solid and cystic lesions of the hand and wrist, few have investigated its accuracy for diagnosing such lesions. The purposes of this retrospective study were to determine the accuracy of sonography for diagnosing focal lesions of the hand and wrist against the standard of histologic examination of the resected specimen and to compare the accuracy of sonography against the recorded initial clinical impression. METHODS: A medical record search for all sonographic studies of the hand and wrist at our institution was performed. Eighty-four patients had correlative surgery and made up the study group. All sonogram reports were reviewed for the absence or presence of focal lesions and specific diagnoses and all medical records were reviewed for the initial clinical impression. Both were compared with histologic findings and tested for agreement with the kappa statistic and for significant differences with the McNemar test RESULTS: Seventy-six of the 84 patients had focal lesions of the hand and wrist and 8 had normal sonograms. Overall, ultrasound correctly diagnosed 83% of the lesions and the initial clinical impression was correct in 54%. Of the 76 lesions ultrasound correctly diagnosed 87% of cystic lesions, 73% of solid lesions, 75% of tenosynovitis cases and the single-vessel thrombosis. The initial clinical impression was correct in 67% of cystic lesions and 75% of tenosynovitis cases. The solid or cystic nature of the 15 solid lesions and the single-vessel thrombosis could not be determined by history or physical examination alone. Of the 35 cases in which the recorded clinical impression was incorrect or not recorded ultrasound provided the correct diagnoses in 71% of these cases. Agreement with the kappa statistical analysis was only fair and the recorded initial clinical impression was less accurate than ultrasound. CONCLUSIONS: Ultrasound was statistically more accurate than the initial clinical impression for distinguishing solid from cystic lesions of the hand and wrist. Ultrasound was very accurate for specifically diagnosing ganglions and slightly less for solid lesions and tenosynovitis.

Adolescent↗
PubMed2004

Giant cell tumors of the tendon sheath: analysis of sonographic findings.

OBJECTIVE: The purpose of this study was to analyze the sonographic characteristics of giant cell tumors of the tendon sheath. CONCLUSION: Giant cell tumors of the hand typically appear as solid, homogeneous hypoechoic masses with detectable internal vascularity that are associated with the flexor tendons of the fingers.

Adolescent↗
PubMed2003

Poverty and common mental disorders in developing countries.

A review of English-language journals published since 1990 and three global mental health reports identified 11 community studies on the association between poverty and common mental disorders in six low- and middle-income countries. Most studies showed an association between indicators of poverty and the risk of mental disorders, the most consistent association being with low levels of education. A review of articles exploring the mechanism of the relationship suggested weak evidence to support a specific association with income levels. Factors such as the experience of insecurity and hopelessness, rapid social change and the risks of violence and physical ill-health may explain the greater vulnerability of the poor to common mental disorders. The direct and indirect costs of mental ill-health worsen the economic condition, setting up a vicious cycle of poverty and mental disorder. Common mental disorders need to be placed alongside other diseases associated with poverty by policy-makers and donors. Programmes such as investment in education and provision of microcredit may have unanticipated benefits in reducing the risk of mental disorders. Secondary prevention must focus on strengthening the ability of primary care services to provide effective treatment.

Developing Countries↗
PubMed2003

Efficacy and cost-effectiveness of drug and psychological treatments for common mental disorders in general health care in Goa, India: a randomised, controlled trial.

BACKGROUND: Common mental disorders are associated with substantial morbidity and disability in developing countries, but there are no data for efficacy of treatment. We aimed to assess the efficacy and cost-effectiveness of antidepressant and psychological treatment for common mental disorders in general health-care settings. METHOD: We did a randomised, placebo-controlled trial (double-blind for the antidepressant group) in general outpatient clinics in two district hospitals in Goa, India. Consecutive eligible adults who scored more than 15 on the Revised Clinical Interview Schedule (n=450) were randomly assigned to antidepressant (fluoxetine), placebo, or psychological treatment. Antidepressant or placebo was provided for up to 6 months. Up to six sessions of psychological treatment were provided by trained therapists. The primary outcome was psychiatric morbidity; secondary outcomes were disability and costs. Outcome measurements were done at 2, 6, and 12 months. Intention-to-treat analyses were done with linear regression. FINDINGS: 80% of patients were reviewed; the number of drop-outs was similar in all three groups. Psychiatric outcome was significantly better with antidepressant than with placebo at 2 months (p=0.02; standardised effect size 0.3), but not over the 2-12 month period (p=0.10); antidepressants were significantly more cost effective than placebo in the short term and long term (p<0.05). Psychological treatment was not more effective than placebo for any outcome during either period. INTERPRETATION: Affordable antidepressants such as fluoxetine should be the treatment of choice for common mental disorders in general health-care settings in India, since they are associated with improved clinical and economic outcomes, especially in the short term.

Antidepressive Agents, Second-Generation↗