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Biomedical subjects

V Wiechmann

Publications and source records attributed to V Wiechmann.

9 recordsLinked to original sources
PubMed2006

[Histological findings for human tibial bone-tendon healing after hamstring transplantation. Investigation of tibial insertion after reconstruction of anterior cruciate ligaments with hamstring transplantation near joint fixation using bioresorbable interference screws].

Ruptures of hamstring reconstructed anterior cruciate ligaments required additional surgery in five cases over a 4 year period. All transplants were primarily fixed with bioresorbable interference screws close to the joint. The average age was 31 years (range: 18-42), the average interval between primary surgery and rupture of the transplant was 13.2 months (range: 8-24) after an adequate re-trauma. After complete removal of the tibial insertion, a histological investigation was carried out. We stained the tissue-sections following the haematoxylin-eosin, Masson-Goldner and van Gieson protocols. All cases revealed direct healing with grow-over Sharpey-like fibers close to the joint, corresponding to a fibrous tendon insertion and far from the joint the formation of fibrous or cartilage callus.

Adolescent↗
PubMed2002

[Pulmonary and pleural metastasis of a malignant granular cell tumor].

HISTORY AND CLINICAL FINDINGS: A 72-year-old woman, who suffered from increasing dyspnea and productive cough was admitted to hospital. Clinical examination revealed a reduced respiratory sounds over the left lung and a painless and unmovable tumor in the area of the left hip. CLINICAL AND LABORATORY TESTS: Apart from hypoxemia (pO2 7.81 kPa) the laboratory values did not indicate any pathological findings. The X-ray and CT-scan of the chest showed a few spotty shadows and pleura effusion on the left. No tumor cells were detected in the pleural effusion. In biopsies of the visceral and parietal pleura as well as biopsy within the tumor in the area of the left hip there were clusters of tumor cells of a granular cell tumor. DIAGNOSIS, TREATMENT AND CLINICAL COURSE: Because the same tumor cell type was detected in the visceral and parietal pleura and wihtin the tumor at the left gluteus area, we diagnosed a malignant granular cell tumor. The CT-scan was suspicious of lung metastasis. The primary tumor was located in the area of left hip. The patient was in a poor general condition and she suffered from an extensive metastastic disease; curative treatment was not possible. A pleurodesis was performed. The patient died nine months after initial diagnosis. CONCLUSION: A rare malignant granular cell tumor was discovered by detecting tumor tissue of granular cell tumor in the pleura and within a tumor in the left gluteus area. Another indication of a metastatic disease were multifocal lesions in the lung detected by CT-scan. Curative treatment was not possible.

Aged↗
PubMed1980

Pulsed Doppler echocardiography for diagnosis of ventricular septal defects.

In order to assess the performance of pulsed Doppler echocardiography and to examine the factors affecting its reliability for the diagnosis of ventricular septal defects, 51 patients, in whom angiographic studies had recently been performed, were investigated before and after operation by this technique. The diagnosis was correct in all cases with left-to-right shunt, when the defect was located either in the upper muscular or in the infracristal portion of the septum, even when pulmonary hypertension or additional cardiac malformations were present. Pulsed Doppler echocardiography did not differentiate between supracristal ventricular septal defects and obstruction of the right ventricular outflow. Apical muscular defects were never observed in our cases. Defects of the inlet portion were not localised by the method. In cases with bidirectional shunt, pulsed Doppler echocardiography failed to provide any diagnostic clue. When a right-to-left shunt was present, only in one case with membranous pseudoaneurysm could pulsed Doppler echocardiography provide an exact description of the haemodynamics before and after operation. In 12 of 22 patients with tetralogy of Fallot, pulsed Doppler echocardiography showed flow tracings possibly related to the septal defect. The site of defect and the extent and direction of intracardiac shunting seem to be the main factors affecting its diagnostic performance in ventricular septal defects.

Doppler Effect↗
PubMed1978

Preliminary experience with the pH-triggered pacemaker.

A cardiac pacemaker capable of responding to blood acidosis by change in its stimulation rate allows adjustment to a patient's metabolic needs. The blood pH is sensed by an iridium oxide electrode in the right atrium. During exercise, the venous pH decreases and the paced ventricular rate increases. If acidosis persists, the paced rate gradually returns to baseline and reaches it after about 70 minutes. A pH-triggered pacemaker has been implanted in a 72-year-old male. The pacemaker remained responsive one year after implant, increasing rate during exercise, cold pressor stress, ischemia of the arms and emotional stress.

Aged↗