[An inhalation glucocorticoid--budesonide].
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Biomedical subjects
Publications and source records attributed to V Vondra.
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The authors assessed the action of drugs against bronchial obstruction induced by inhalation of pollen allergen in 54 patients during the symptom-free period of bronchial asthma. Protection against pollen allergen was provided by disodium cromoglycate (Intal-nasal)--20 mg--in 96% of patients (P less than 0.001), by beclomethasone dipropionate (Becotide)--400 microgram--only in 17% of the investigated subjects (effect is not statistically significant) and by the antihistamine preparation Dithiaden administered by the i. v. route, 1 mg, in 46% of the patients (P less than 0.01). The authors made a detailed statistical analysis and discuss the causes of different results as regards the protective action of the investigated drugs.
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