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Biomedical subjects

V Vladyka

Publications and source records attributed to V Vladyka.

At least 55 records · Page 3Linked to original sources
PubMed1984

Nocturnal sleep stereo-electroencephalography and polygraphy in epileptics.

Focal epileptic activity (FEA) in amygdalohippocampal complexes (AHC) is mostly highly intensive (except in patient BUK where it is nearly missing). Unilateral FEA is hardly ever propagated to the superficial EEG electrodes, bilateral FEA only very rarely (patients BRY and DUS), in some patients solely in deep synchronous sleep (patient LOB). FEA intensity rises in relaxed vigilance and in superficial sleep while tending to decrease in deep synchronous sleep. FEA intensity tends to drop or even disappear in active vigilance during mental activity or paradoxical sleep. Epileptic activity generalized in all the superficial and deep-implanted leads is mostly accompanied by clinical manifestations (absences, twitching, motor automatisms), or to put it the other way round: if a clinical paroxysms is in progress, there is evidence of generalized epileptic activity in all the leads. The time parameter is of no consequence, the inconspicuous motion of the hand is due to a second-lasting discharge of polyspike and wave (patient BRY in sleep). If prolonged discharges remain localized there is subclinical paroxysm (patient IRL). Similar findings were reported by Lieb et al. (1976). All we can add is that the start of an attack depends not only on the amplitude and frequency of the spikes but also on the regularity of spike intervals. Superficial "neocortical" EEG and deep "paleocortical" SEEG exhibit equal sleep stages equally, i.e. either there is synchronization in all the leads (like in synchronous sleep), or there is desynchronization (such as in active vigilance or in paradoxical sleep); those two cortical structures are not antithetical such as in, e.g., rats or cats. The sleep stages show quantitative as well as qualitative changes. There is increasingly more wakefulness and superficial sleep at the expense of spindle and paradoxical sleep. EEG graphoelements often show little differentiation, e.g. the sleep spindles are short and irregular in shape, delta activity is low in amplitude and also irregular in shape, and paradoxical sleep shows insufficient desynchronization in EEG and preserved tonic muscular activity. Epileptic activity variability is often found helpful for the reliable identification of the sleep stage concerned.(ABSTRACT TRUNCATED AT 400 WORDS)

Adolescent↗
PubMed1981

Surgical possibilities for alleviation of axial dyskinesias - comparison with forced movements of the head and eyes.

107 patients suffering from axial dyskinesias (torticollis and torsion dystonia) were observed at our clinic over a period of 10 years. In 15 patients, stereotactic lesions involving the head-turning bundle at the caudatocapsular level, which mediates forced adversive movements, were performed. In 70% good to excellent results were confirmed. However, differences between forced adversive movements and torticollis were identified. There are striking motor and motivational similarities between torticollis and ritualized fixed action patterns of low-ranking subjects. The aetiology of axial dyskinesias, especially of torticollis, is multifactorial, long-term psychic stress being an important factor. The relationship of axial dyskinesias, especially of torticollis, to compulsive neuroses is discussed, and Mazar's 'adversive' target area is identified as a partial orbitomedial leukotomy.

Adult↗