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Biomedical subjects

V Vasilescu

Publications and source records attributed to V Vasilescu.

At least 55 records · Page 3Linked to original sources
PubMedDate not supplied

Studies concerning ATP dynamics in essential hypertension.

The use of Beckmann LS-7000 liquid scintillation spectrometer enabled us to develop a rapid and reproducible technique for the enzymatic microdosage of ATP by means of the bioluminescence reaction of the luciferin-luciferase system from the firefly. Changes of ATP concentration in the plasma, erythrocytes and cerebrospinal fluid of the hypertensive subjects as compared to the control ones have been revealed by means of this method. According to our results ATP concentration significantly increases in the plasma and cerebrospinal fluid and slightly modifies in the erythrocytes of the hypertensive as compared with control subjects. Correlation of data concerning the variation of ATP distribution in the different compartments (plasma, erythrocytes, cerebrospinal fluid) with those related to Na and K content in hypertensive and control subjects seems to be useful for some remarks on the molecular mechanisms in the essential hypertension.

Adenosine Triphosphate↗
PubMedDate not supplied

The structure-function relationships in the ionic channels of the axonal membranes as revealed by deuteration.

The present study has two purposes: c) to summarize our most important experimental results concerning the deuteration effects on the Ranvier node membrane as well as those obtained by others on the giant axons; ii) to reveal the significance of the macroscopic-microscopic correlations reflected in the excitation processes which underlie the ionic channel behaviour and for which deuteration has provided a new alternative of investigating the molecular mechanisms.

Animals↗
PubMedDate not supplied

Dynamics and compartmentation of water in certain biosystems.

Investigation performed by nuclear magnetic resonance and by deuteration on the dynamics of water molecules in mammalian blood cells and in amphibian oocytes, muscles and nerves allowed to reveal several populations of cell water molecules. Following up relaxation and exchange processes in cell suspensions, packed cell pellets and in isolated tissues, characteristics of water dynamics and compartmentation in various biosystems are compared.

Animals↗