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Biomedical subjects

V Valenza

Publications and source records attributed to V Valenza.

51 records · Page 3Linked to original sources
PubMedDate not supplied

[Scintigraphic diagnosis of Meckel's diverticulum using Tc-99m-pertechnetate].

Meckel's diverticulum (MD) is a well-known cause of lower gastrointestinal hemorrhage, particularly in the pediatric age group. The radionuclide 99mTc-pertechnetate has been found useful in visualizing MD which contain gastric mucosa. This test is predicated of the affinity of the isotope for the parietal cells of the gastric glands. In an attempt to evaluate the sensibility and specificity of pertechnetate, the clinical data and scintigrams of 27 patients with suspected MD were reviewed. The scintigram correctly identified MD before operation in 6 of 7 patients. The false negative study occurred in a MD without gastric mucosa.

Adolescent↗
PubMedDate not supplied

[Practical use of the Möhr and Johnson formula for calculation of ideal weight. Preliminary observations on deviations from ideal weight in a group of 1,000 Sicilian adults].

Simplification of the operations required for the calculation of ideal weight in adults in accordance with the formula of Möhr & Johnsen is suggested. Preliminary notes on a group of 500 male and 500 female Sicilians aged 18-24 following determination of the Strömgren metrical index and somatotype, ideal weight, and a variation index of differences between the real weight and the ideal weight are presented. Leptomorphs were clearly predominant, particularly among the males. Assessment of the variation index values for each subject within the different somatotypes was followed by analysis of the frequency distribution of under-, normal, and over-weight subjects. Percent frequency was noticeably asymmetrical, with marked differences between somatotypes and the sexes, though there was a clear ratio between deviation and somatotype features. The overall percent frequencies without reference to somatotype were slightly more symmetrical and lay on a leptokurtic curve.

Adult↗
PubMedDate not supplied

The prenatal morphology of the articular disk of the human temporomandibular joint.

The prenatal morphology and ultrastructural of the articular disk of the human temporomandibular joint was studied to determine their relationship to the corresponding adult characteristics. The articular disks of seven human fetuses ranging in age from 10 to 32 weeks' gestation were examined. Our results show that the fetal articular disk has a genetically pre-determined appearance that substantially prefigures that of the adult. In profile, it was seen to be thin at the center and thick toward the periphery, like the adult structure; likewise, it was denser centrally than peripherally. Basically, it was found to be a fibrous structure: it was composed of a large number of connective tissue cells, while the blood vessels were limited to the periphery. A large number of elastic fibers was also observed. Posteriorly, they had a longitudinal orientation along the junction with the postglenoid tubercle of the temporal bone; along the periphery, they ran in an annular fashion.

Cartilage, Articular↗
PubMedDate not supplied

Is there still a role for functional radionuclide study of the liver?

Clinical applications of radionuclide methods for the study of liver hemodynamics and hepatocyte function are examined. In particular, as for hemodynamic studies, perfusion assessment with radiocolloids, 99mTc-IDA scintigraphy or 99mTc-labeled red blood cells, is underlined; they allow characterization of the different cellular component of space-occupying liver processes. The use of hepatic perfusion index (HPI) is reconsidered both as prognostic parameter in cirrhotic patients and as predictor of liver metastasis from colorectal cancer. The diagnostic role of recent procedures, as those based on endorectal radiopharmaceuticals in the evaluation of portosystemic shunts in cirrhosis, is analyzed. Studies of hepatocyte function of practical concern are essentially devoted to the "excretory function" and "asialoglycoprotein metabolism". In the first case, a major role is played by IDA halogenated derivatives and functional parameters drawn from them by mathematico-statistical evaluations of radiohepatogram (simple or applied to compartmental models). For metabolic studies, at present an artificial glycoprotein, 99mTc-galactosylneoglycoalbumin (99mTc-NGA) that binds with hepatocellular receptors is used. Information on the rate of blood plasma clearance and liver uptake, receptor density (altered in some pathologic conditions) and plasmic hepatic flow, is supplied.

Adult↗