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Biomedical subjects

V V Vasil'ev

Publications and source records attributed to V V Vasil'ev.

At least 19 recordsLinked to original sources

[Direct results of endovideosurgical transabdominal adrenalectomy].

Results of transabdominal adrenalectomy performed in 29 patients with different tumors of the adrenals were estimated. The lower traumaticity of the access due to using a new technology as well as taking prophylactic measures for lower aggressive influence of the pneumoperitoneum allowed performing combined operative interventions in 30% of cases and avoiding serious intra- and postoperative complications.

Abdomen↗

[Decision for the method of surgical treatment of acute destructive pancreatitis].

The work presents results of treatment of 375 patients with acute pancreatitis, 93 patients with destructive pancreatitis were operated upon. Minimally invasive and traditional technologies were used. Postoperative lethality was 6.5%. The method of lumboscopic extraperitoneal drainage of the destruction focus under the control of laparoscopy and USI is described. The percutaneous paracenthetic-draining interventions under the control of USI and endovideosurgical technologies were shown to be highly effective in treatment of patients with acute destructive pancreatitis and its complications.

Decision Making↗

[Diagnosis and choice of the method of surgical treatment of pancreatic cysts using ultrasonic examination].

A more than 10 year experience of using operative interventions under the control of ultrasound has shown that in order to solve the task of improving the results of surgical treatment of cysts of the pancreatic gland it is necessary to improve a number of diagnostic and organizational measures allowing to perform the early and effective diagnosis of the cysts and their timely treatment. The percutaneous puncture-drainage operations with sclerotherapy are indisputably considered to be highly effective in treatment of cysts of the pancreas. In most patients, however, the clinical and ultrasonic signs of pancreatitis are still retained. These patients need permanent dynamic observation and conservative therapy.

Adolescent↗

[Evaluation of the functional state and working capacity of patients with chronic toxoplasmosis].

Operator's main functions were studied in 78 patients with chronic toxoplasmosis during the period of disease aggravation and during the following 6 months. It was revealed that marked disorders in higher nervous activity and psychomotor system are observed in the patients during the period of aggravation, significantly more expressed during disease recurring course. It is reasonable to examine servicemen with chronic toxoplasmosis using psychologic and psychophysiologic methods before treatment and in 6 months after its completion. Without clear tendency towards improvement of professionally significant qualities in 6 months after treatment (level of neurotization, psychopathyzation, comparative number of mistakes in attention test and during reckon in head, delayed memory, positive tapping-test) it is not recommended to use servicemen at the posts having operator's profile and connected with long staying in secluded small collectives.

Adult↗

[A methods of laparoscopic suturing of perforated pyloro-bulbar ulcers].

The article describes a method of laparoscopic suturing perforated ulcers of the pylorobulbar zone. The elements of all steps of the operation are analyzed including the places of introducing the trocar, the method of putting the intracorporeal stitches, means of sanitation and drainage of the abdominal cavity. The method was successfully used in operations on 43 patients with perforated ulcers without any complications.

Adolescent↗

[The immediate results of laparoscopic treatment in perforated gastroduodenal ulcers].

The article presents an analysis of immediate results of laparoscopic interventions (suturing, vagotomy) in 40 patients with perforated ulcers in the pylorobulbar zone. Postoperative complications were noted in 7.5% of the patients. There were no lethal outcomes. The authors recommend wider introduction of the laparoscopic technology as a method of optimization of surgical treatment for perforated ulcers.

Adolescent↗

[Use of laparoscopic methods in combined surgery].

The authors have made a comparative analysis of the effectiveness of isolated and combined laparoscopic cholecystectomies. The control group consisted of 246 patients subjected to isolated cholecystectomies. The group under study included 22 patients in whom combined cholecystectomies were performed. The comparative analysis included the following clinical data: duration of the operation, number of postoperative days in the hospital, amount of postoperative complications. It was concluded that the little-invasive laparoscopic technique used in one of the steps of the combined operation allowed traumatism of the surgery to be decreased which in its turn allowed wider indications to combined operations.

Adult↗

[Late results of combined surgery of the veins and lymphatic vessels in patients with chronic lymphovenous insufficiency of the leg].

An analysis of long-term results of treatment of 1258 patients with chronic lymphovenous insufficiency of lower extremities has shown the necessity of differentiated approach to different categories of the patients. A substantial improvement of results of the treatment of patients with complicated forms of varicose disease is observed in combination of operations on the venous and lymphatic systems. The character of these operations (lymphovenous anastomoses, lymphonodovenous anastomoses) must be determined strictly individually on the basis of an analysis of clinical course of the disease, data of lympho- and phlebography.

Anastomosis, Surgical↗

[Characteristics of the thrombohemorrhagic syndrome in patients with systemic lupus erythematosus].

The authors analyzed data of the clinical picture and autopsy results in 26 patients with systemic lupus erythematosus. During life hemorrhagic complications were revealed in 19% of patients, thrombotic--in 12%, while pathoanatomically they were found correspondingly in 46% and 27% of cases. In 15% of cases thromboses and hemorrhages were registered simultaneously. An interrelationship was noted between the activity of the disease and frequency of hemorrhagic complications as well as between the duration of the disease and quantity of thrombotic complications.

Adolescent↗

[Unpaired bases in the B--Z junction of the supercoiled plasmid].

The restriction analysis has been used to establish that O-beta-diethylaminoethylhydroxylamine (OHA) produces modification of unpaired cytidines in the polylinker region adjacent to the Z-insert (dG-dC)10. (dG-dC)10 in the negatively supercoiled plasmid pGC20. The length of the transition region between B- and Z-portions of DNA is not less than 36 bps. The reaction of OHA with the unpaired cytidines in the B-Z junction is a fixing one and produces no secondary despiralling of the neighboring regions. The reaction with DNA proceeds much slower than the one with monomers and single-strand polynucleotides. The structural nonuniformity has been observed, which is manifested in the alternating B and "non-B" form DNA in the B-Z junction. It is suggested that these junctions may contain nucleotide sequences which are stable to violation of the B structure during the change in superhelical density of DNA.

Base Sequence↗

[Cloning in cells of Bacillus subtilis and study of the characteristics of promoter regions of DNA of Bacillus mesentericus and Phage SPO2].

11 fragments of Bacillus mesentericus and phage SPO1 DNA containing promoters were cloned in Bacillus subtilis. Nucleotide sequences of these fragments were determined and S1 mapping of transcriptional start points was performed. It was found that some fragments contained tandem or overlapping promoters. Nucleotide sequences of Bacillus mesentericus promoters were compared with known promoters from bacilli. Promoter activities were determined in different phases of cell growth. Nucleotide sequences of several promoters coincided with known sigma 43, sigma 29, sigma 28-promoters. Nucleotide sequences of other promoters differ greatly from those used by the known forms of Bacillus subtilis RNA polymerase. The existence of at least four other forms of bacilli RNA polymerase specific for these promoters is suggested.

Bacillus subtilis↗