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V V Talantov

Publications and source records attributed to V V Talantov.

17 recordsLinked to original sources
PubMedDate not supplied

[Changes in the sensitivity of lipoatrophic tissues to insulin under the effects of novocaine].

A study was made of the isolated adipose tissue of 9 healthy women and the adipose tissue from the zone of lipoatrophy obtained from 7 women suffering from diabetes mellitus treated with insulin. In difference to the adipose tissue of healthy persons, in the lipoatrophic adipose tissue there occurred under the effect of insulin-novocain mixture a marked increase in the incorporation of C-14-labeled glucose into the total lipids of the adipose tissue. The data obtained served as an argument in favour of the neurotrophic genesis of the postinjection insulin lipoatrophies and proved the neuro-trophic mechanism of the therapeutic effect of the insulin-novocain mixture.

Adipose Tissue↗
PubMedDate not supplied

[Status and prospects of the problem of endemic goiter].

The paper is concerned with the clinical problems of endemic goiter control. The stabilization of prevalence of thyroid hyperplasia has been shown as a result of underestimation of other than iodine deficiency giterogenic factors. Functional essence of the disease, a tendency to hypothyrosis, have been unraveled. Organizational problems and prospects of research in this area are considered.

Adult↗
PubMedDate not supplied

[Postinjection changes in angiopathy patients].

The results are presented of studying the response of the foot skin blood microcirculatory vessels after injecting 2ml of saline solution of NaCl into the hip. A group of patients with diabetes mellitus aggravated by angiopathy of low extremities was managed with insulin during 4 to 18 years and examined versus insulin-untreated diabetes mellitus patients, persons with low limb obliterating thromboangiitis and healthy volunteers. The studies were carried out, using the "skin window" method, which allows one to investigate not only the capillary function but also the state of other skin microcirculatory units. It was determined that at rest the functioning microvessel density per the tissue area unit is compensatory enhanced in patients with angiopathy. The pain irritating effect (the injection) is integrated into a stereotypic vasospastic response in all the persons under study, becoming pathologically persistent in patients with angiopathy. It was concluded that the maximum tissue sparing is necessary during the injection therapy, considering this procedure as a factor of arising and developing the vessel affection, especially in diabetes mellitus insulin-treated patients, subjecting to systematic insulin injections.

Adult↗