Search PubMed⌕ Search

Biomedical subjects

V V Osipova

Publications and source records attributed to V V Osipova.

14 recordsLinked to original sources
PubMed2006

[Migraine and "sleep-wake" cycle].

The results of the comparative analysis of patients with migraine attacks developing in the waking period (AP) and night sleep period are presented. Patients with sleep-related migraine (SM) had higher levels of depression and anxiety, marked autonomic dysfunction and stable sleep disturbances that resulted in significant maladaptation of these patients in the between-attacks period and low quality of life. Depression plays a role in the transformation of AP to SM and formation of stable sleep disturbances in the between-attacks period in patients with SM. It is suggested that common serotoninergic mechanisms involved in migraine attack may contribute to formation of "sleep-wake" cycle and depression development. The principles of optimal therapy of such patients are formulated.

Adult↗
PubMed2003

[Gender differences in migraine and wake-sleep migraine attacks].

A follow-up clinical study was made of 320 patients examined in Autonomic Pathology and Headache Center, Nervous disease clinic, Sechenov Moscow Medical Academy, since 1989 to 1999. The peculiarities of migraine attack course and remission period, psychological characteristics, concomitant diseases and quality of life in men and women were described. In women, migraine attacks were more typical, prolonged and severe, being often stipulated by provoking factors, especially by emotional ones, as well as accompanied by autonomic disturbances, anxiety and depression. Despite a more favorable migraine course, men proved to score lower on quality of life, revealing more maladaptation. Patients with sleep migraine attacks were distinguished by more severe migraine course, multiple disturbances in remission period, higher depression and anxiety levels, as well as lower quality of life. Common serotoninergic mechanisms were suggested to underlie sleep migraine and depression. The leading role of depression in the origin of night migraine attacks is discussed.

Adult↗
PubMed2003

[Hemodynamics, electrophysiological parameters of the heart and differential therapy of attacks of atrial fibrillation in patients with subclinical thyroid dysfunction].

Thirty patients with subclinical thyrotoxicosis and 32 with subclinical hypothyroidism with attacks of atrial fibrillation were investigated. At levels of thyroid-stimulating hormone below 0.1 or above 10.0 mIU/l average triiodothyronine and thyroxine levels in patients with subclinical thyrotoxicosis were 89.6 and 73.2%, respectively, higher than in patients with subclinical hypothyroidism. Some relationships were found between levels of thyroid hormones and hemodynamic and electrophysiological parameters of the heart. Differential therapy of attacks of atrial fibrillation was effective in 80 and 62.5% of patients with subclinical thyrotoxicosis or hypothyroidism, respectively.

Adult↗
PubMed2002

[Clinical and psychological analysis of migraine population].

The study presents a clinical analysis of a large population of migraine patients (n = 320). Computed database used in the study included over 100 clinical parameters and was based on analysis of primary medical records. As a result of statistic processing of the migraine archive, a general review of clinical picture and migraine course in patients from Moscow and Moscow region community and analysis of the peculiarities of migraine heredity, concomitant symptoms, provoking factors, co-morbid diseases, state in attack-free period, psychological characteristics and quality of life are provided. Factors determining course severity and quality of life in migraine are discussed.

Adult↗
PubMed2001

[Clinical and psychological characteristics and therapy of patients with cluster (bunch) headache].

The paper presents a discussion on clinical psychological peculiarities of patients with cluster headache (CHA), an analysis of these data in dependence on CHA form (episodically or chronically), on the sex of the patients, on the side of the headache localization (right-sided, left-sided). Taking into consideration a correlation of the headache attacks and the quality of the night sleep, the therapy with imovan (zopiclone) preparation was proposed. Such therapy resulted in positive changes including disappearance of the night attacks and the decrease of the intensitivity of the algesic attacks during daily time.

Adult↗
PubMed1991

[Evaluation of the autonomic innervation of the pupil].

The purpose of the study was to examine vegetative innervation of the pupil in different diseases associated and not associated with vegetative disorders. In addition to the ++clinico-neurological method, the main method of examination was to study the pupillary cycle (determination of the time of the pupillary cycle (TPC) with the aid of a slit lamp). Fifty healthy test subjects and 262 patients suffering from different somatic and neurologic diseases were examined. The patients were divided in 9 clinical groups: spinal amyotrophy, neural Charcot-Marie amyotrophy, Guillain-Barre syndrome, diabetes mellitus, thyrotoxicosis, hemicrania, Raynaud's disease, idiopathic hyperhidrosis, vegetative crises. The data obtained demonstrate varying grades of the rise of the TPC in the indicated diseases, which reflects varying degrees of vegetative innervation of the pupil insufficiency. However, no well-defined correlation was obtained between the intensity of the psychovegetative syndrome and the TPC. Therefore, it has been shown that the method of determining the TPC is unsophisticated and noninvasive and can be successfully used in different forms of pathology to identify vegetative insufficiency at different stages of the disease.

Autonomic Nervous System Diseases↗
PubMed1991

[Clinical aspects and treatment of migraine].

The paper is concerned with clinical, therapeutical and classification problems of migraine. A "vegetative" form of migraine is distinguished characterized by a vegetovascular crisis in the disease episodes. Clinico-psychophysiological characteristics are provided for 30 patients with common and 40 with vegetative migraine. The latter run seems more severe with frequent episodes, permanent vegetative disorders in the episodes-free period, marked emotional symptoms (hypochondriac, demonstrative and anxious). In addition to clinico-neurological, questionnaire and thermographic methods, the study employed visual analog pain scale, tests of segmentary vegetative apparatuses (6 cardiovascular tests and time of pupil cycle), psychological tests (MIL, Spilberger's). Differential approaches to migraine forms are advocated, basic principles of optimal therapy of migraine cephalalgia are formulated.

Adrenergic beta-Antagonists↗