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V V Natarov

Publications and source records attributed to V V Natarov.

24 records · Page 2Linked to original sources
PubMedDate not supplied

[Characteristics of the clinical aspects, and hormonal and immunological status of thyrotoxicosis patients with a hereditary predisposition to endocrine diseases].

The levels of triiodothyronine (T3), thyroxine (T4), TTH, STH, free triiodothyronine index T3F/T3/T4, as well as the titers of antibodies to microsome-membranous antigen and thyroglobulin, were studied in thyrotoxic patients with hereditary predisposition to endocrine diseases (thyrotoxicosis, goiter, diabetes mellitus) and in subjects without such heredity. Peculiarities of the disease development and endocrinopathy distribution among their relatives were investigated. More pronounced disorders in thyroid hormone metabolism and humoral immunity state were seen in thyrotoxic patients with hereditary predisposition to endocrine diseases. In comparison with those of the subjects without this heredity. The risk of diabetes mellitus development was detected in thyrotoxic patients predisposed to diabetes mellitus. Clinical manifestations of thyrotoxicosis (the disease severity, goiter of the IVth sage, exophthalmos) were also more evident in subjects predisposed to endocrine diseases.

Adolescent↗
PubMedDate not supplied

[Prolactinemia in thyrotoxicosis].

Prolactin, triiodothyronine, thyroxin and thyrostimulating hormone content was determined in juvenile and middle-aged females with preserved menstrual cycles by radioimmunoassay. The indices studied were shown not to be dependent on the menstrual cycle phase (P greater than 0.05). In patients with thyrotoxicosis, a remarkable increase in prolactin level, which correlated with triiodothyronine content, was observed.

Adolescent↗
PubMedDate not supplied

[Sex differences in the consequences of the hormonal treatment of male rats for their progeny].

The effects on male rats of single injections of androgens have been shown; this paper considers the responses of the immune and genital systems. The consequences for the progeny, with special reference to their sex and age, of androgenization of the father are considered in a comparative aspect. Deviations have been recorded in physical and sexual development, as well as in the genital system, in the progeny of both sexes. Furthermore, the male progeny is characterized by increased reactivity of the thymus.

Adrenal Glands↗
PubMedDate not supplied

[The efficacy of replacement therapy in hypothyroidism].

The use of L-thyroxin in the substitution therapy for hypothyrosis is, in our judgement, a most pathogenetically well-grounded option. In the early period of the treatment of hypothyrosis with L-thyroxin the total clearance of thyroxin is accelerated and is in inverse relationship to the initial blood hormone level. From the results of pharmacokinetic studies a specific individualized regimen is proposed of thyroxin administration in the early period of the treatment of hypothyrosis, which allows the thyroxin concentrations to be achieved within the range of 120-150 micrograms. The use of the above method results in clearing up pathognomonic symptomatology of hypothyrosis, normalization of the thyrotrophin and total cholesterin levels, improvement in central hemodynamics in 14-21 days, promotes complete rehabilitation of patients about 1 month after the initiation of treatment.

Adult↗