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Biomedical subjects

V V Maleev

Publications and source records attributed to V V Maleev.

At least 91 records · Page 5Linked to original sources

[Various characteristics of the thrombohemorrhagic syndrome in a generalized form of meningococcal infection complicated by toxic-infectious shock].

Blood coagulation was studied in 19 patients with generalized meningococcal infection complicated by toxico-infectious shock (TIS). The outcomes were fatal in 42% of cases. Blood coagulation studies were done on days 1, 2, 3, 5-7 and 19-21 of treatment. Blood coagulability was found to be reduced drastically at the peak of disease: platelet aggregability was depressed substantially, and platelet secretory function showed profound disorders. The recovery of both plasma and platelet parameters of blood coagulation was rather slow. The magnitude of disorders may have a predictive value for the prognosis of the disease.

Adolescent↗

[Action of toxic staphylococcal (St. aureus) substances on the functional properties of the thrombocytes].

The effect of toxic substances from St. aureus on morphofunctional properties of platelets has been studied in vitro. The toxic substances have been shown to induce platelet aggregation and stimulate their secretion. The platelets are transformed from discs to spheres with small pseudopodia. It is believed that platelet aggregation and secretion play an essential role in hemostasis and microcirculation disturbances.

Acridine Orange↗

[Diagnosis of Grigor'ev-Shiga dysentery].

The data on the relative significance and composition of Sh. dysenteriae serovars isolated in some regions of the USSR in 1975-1979 are presented. Special tests revealed that Endo agar was the best medium, while Ploskirev's agar was the worst medium for growing Sh. dysenteriae 1 (the museum strain and the newly isolated strain from Bangladesh). The testing of agar with eosine-methylene blue yielded moderate results in respect of the growth of the museum strain; as to the growth of the strain from Bangladesh, the results were identical to those obtained in testing Ploskirev's agar. The "epidemic" strain from Bangladesh was shown to correspond to the classical characteristics in its fermentative properties: polyvalent dysenteric phage and agglutinating sera produced in the USSR proved to be completely suitable for identification. The present-day clinical course and clinico-laboratory characteristics of dysentery caused by Sh. dysenteriae 1 are described. Practical recommendations on the bacteriological and clinical diagnosis of Grigoryev-Shiga dysentery, brought from an outside infection source, are proposed.

Agglutination Tests↗