Biomedical subjects

V Tzingounis

Publications and source records attributed to V Tzingounis.

24 records · Page 2Linked to original sources

PubMed1979

Role of the hypothalamus in the aging woman.

Relationships between the hypothalamus and the pituitary in the aging woman are discussed under the following subheadings: synthesis and release of follicle-stimulating and luteinizing hormones, estrogen receptors, other releasing factors, neurotransmitters, and the mechanisms of hot flushes and migrainoid headaches. The hypothalamus is the main regulator of pituitary function. In the female the hypothalamic-pituitary axis appears to remain functionally intact well into old age.

Aged↗

PubMed1978

Maternal serums and amniotic fluid levels of human placental lactogen in gestational diabetes.

Human placental lactogen (hPL) levels were measured radioimmunologically in maternal serum and in amniotic fluid between the 37th and 39th weeks of gestation in sixteen gestational diabetic and thirty normal pregnant women. There was no significant difference in maternal serum hPL levels between diabetic (6.1 microgram/ml) and normal pregnant women (6.4 microgram/ml). In contrast, the diabetic group was found to have significantly (P less than 0.001) higher concentrations of amniotic fluid hPL (1.2 microgram/ml) than normal pregnant women (0.8 microgram/ml).

Amniotic Fluid↗

PubMed1978

Amniotic fluid, maternal and fetal blood insulin in overweight pregnant women.

The effect of excessive maternal weight gain on insulin levels during pregnancy (15 cases) was compared with the insulin levels in a control group (20 normal pregnancies) by radioimmunologic determination of insulin in the amniotic fluid and in maternal and fetal blood. The mean values of insulin in the control group were as follows: mother 24.9 +/- 0.51, fetus 10.86 +/- 0.48 and amniotif fluid 6.08 +/- 0.42 muU/ml, and in patients with excessive weight gain during pregnancy, maternal insulin mean values were 39.45 +/- 1.86, fetal 20.99 +/- 3.39 and amniotic fluid 12.25 +/- 1.15 muU/ml. Insulin concentrations in maternal blood (P less than 0.001), fetal blood (P less than 0.001) and amniotic fluid (P less than 0.001) were higher in excessive weight gain pregnancies as compared to the control group.

Amniotic Fluid↗

PubMed1977

Insulin levels in the amniotic fluid and in maternal and fetal blood.

The effects of excessive maternal weight gain during pregnancy (five cases) and of glucose infusion in the mother (five cases) on insulin levels are compared with the insulin levels in a control group (19 normal pregnancies) by radioimmunologic determination of insulin levels in the amniotic fluid and in maternal and fetal blood. The mean values for insulin in the control group were as follows: mother, 23.9 +/- 2.23 muU per ml; fetus, 9.86 +/- 2.11 muU per ml; and amniotic fluid, 5.08 +/- 2.27 muU per ml. In patients with excessive weight gain during pregnancy, maternal insulin mean values were 38.45 +/- 4.16 muU per ml; fetal, 19.99 +/- 9.8 muU per ml; and amniotic fluid, 11.25 +/- 2.58 muU per ml. After an infusion of 25 mg of glucose in the mother, the mean maternal insulin values were 53.6 +/- 13.74 muU per ml; fetal, 24.7 +/- 6.67 muU per ml; and amniotic fluid, 14.3 +/- 5.52 muU per ml. Insulin concentrations in maternal blood (p less than 0.001), fetal blood (p less than 0.001) and amniotic fluid (p less than 0.001) were higher in pregnancies with excessive weight gain as compared to those in the control group, whereas the glucose infusion in the mother increased the concentration of insulin in the three components studied.

Amniotic Fluid↗

PubMedDate not supplied

Radiographic abnormalities in patients with Stein-Leventhal syndrome.

Radiographic abnormalities in 254 patients with Stein-Leventhal syndrome are presented in a retrospective study of the six-year period from 1972--1977. Twenty-two (8.7%) of the patients were found to have abnormal sella turcica x-rays, eight (3.2%) patients had abnormal hysterosalpingograms and five (2.0%) patients had abnormal intravenous pyelograms. In addition, three patients with an abnormal sella turcica had serum prolactin levels greater than 45 ng/ml, which should be regarded as evidence of a pituitary adenoma. These findings suggest that serum prolactin assays and skull x-rays with polytomography should be routinely performed on patients with Stein-Leventhal syndrome.

Female↗

PubMedDate not supplied

Incidence of benign and malignant breast disorders in women taking hormones (contraceptive pill or hormonal replacement therapy).

The incidence of breast disorders, in a series of 142 women of reproductive age who received combined oral contraception (OC) for birth control and in 98 postmenopausal women who received hormone replacement therapy (HRT) with estrogens and progestins, for seven years, was compared with control groups. A lower incidence of benign breast diseases was observed among OC users (p < 0.001) and HRT recipients (p < 0.001). No differences were observed in the incidence of breast cancer among the groups studied. OC use and HRT do not increase the risk for breast cancer and decrease the incidence of benign breast diseases.

Adult↗