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Biomedical subjects

V Trnka

Publications and source records attributed to V Trnka.

At least 73 records · Page 4Linked to original sources
PubMed1977

Screening of amino acid enzymopathies in pregnancy and possibilities of their prenatal diagnosis.

The report discusses the first results obtained by chromatographic screening of the blood amino acids in pregnant women at the outset of pregnancy. Typical cases of maternal phenylketonuria and maternal hyperphenylalaninaemia found among 2,000 women examined are described in detail, giving a concise metabolic, clinical and genetic picture. The biochemical possibilities of diagnosing congenital disorders of amino acid metabolism before birth are also discussed.

Amino Acid Metabolism, Inborn Errors↗
PubMed1975

[Determination of the nucleolar coefficient in lymphocytes in chemotherapeutically treated patients with ovarian carcinoma].

At the total evaluation of the base values of lymphocytes in the patients with Ca ovariorum a lower number of lymphocytes was found than in the healthy population. At the same time the lymphocytes in the patients with Ca contained a lower number of nucleoli which are capable of the synthesis RNA (i.e. nucleoli ringsingers and active) and a higher number of nucleoli irreversible unable of the synthesis of RNA, i.c. micronucleoli. So the value of the nucleolar coefficient was rised, too, in these patients. It seems, that the described changes were dependent of the clinic condition of our patients, in some cases they preceded the state. This method is utilised at the IInd Obstetric Gynaec. Clin. in Prague for the long time cytostatic therapy.

Acrylates↗