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Biomedical subjects

V Trischitta

Publications and source records attributed to V Trischitta.

79 records · Page 5Linked to original sources
PubMedDate not supplied

[Chronic obstructive bronchopneumopathy and ectodermal dysplasia].

A boy, 5 year aged, admitted in intensive therapy room because affected by respiratory insufficiency, is reported. Recurrent lower respiratory tract infections and three surgical operation in the lacrimal ducts were present in the anamnesis. Clinical and radiologic features of chronic obstructive pneumonia were present. Hypotrichosis, onychodystrophy, microdontia, associated with absence of muciparous glands and greatly reduced muciparous cells of respiratory tract, were other findings.

Bronchi↗
PubMedDate not supplied

[Toxic epidermal necrolysis and immunologic disorders].

The authors describe a "boiled baby", 17 months aged. The condition started acutely as an intense erythema that quickly progressed to blistering. The clinical appearance and symptomatology evoked a scalded skin. The entire cutaneous surface suffered the process. The lesions appeared after herpes-infection and were followed by knee arthritis and bronchial pneumonia. Laboratory patterns showed immunologic disorder.

B-Lymphocytes↗
PubMedDate not supplied

[Blood gas analysis and evaluation of pulmonary functional damage in bronchiolitis].

212 Sucklings affected with bronchiolitis were evaluated monitoring values of haematic gases and acid-base balance. The patients were differentiated in three groups: Hypoxemia--Hypercapnia (3.7%). Hypoxemia--Normocapnia (38.2%). Normoxemia--Hypocapnia (58.1%). Metabolic acidosis was detected in 55.1% of cases. The different value of haematic gases was correlated with entity of the pulmonary functional damage.

Acidosis, Respiratory↗
PubMedDate not supplied

[Biochemical monitoring of the insufficient systemic perfusion in bronchiolitis].

Biochemical monitoring was performed on 113 sucklings affected with bronchiolitis in order to evaluate early onset of insufficient systemic perfusion. Values of haematic lactate, GPT and CPK levels in the serum, partial tension of haematic gases were evaluated on first day of hospitalization. Haemogasanalytic monitoring made it possible to differentiate two groups of infants: 21 patients with hypoxemia and 92 patients with normoxemia. Monitoring of lactatemia, CPK and GPT activity evidenced following values: hyperlactemia (66.6%), increased CPK levels (47.6%), increased GPT levels (14.2%) in the group of infants with hypoxemia. Hyperlactemia (55.4%), increased CPK levels (62%), increased GPT levels (19.5%) in the group of patients with normoxemia. These findings show no significant difference between the two groups and frequent occurrence of tissular hypoxia attributable to insufficient systemic perfusion. Moreover the results of such biochemical monitoring permit precise indication about appropriate treatment.

Alanine Transaminase↗
PubMedDate not supplied

Effects of biguanides and sulfonylureas on insulin receptors in cultured cells.

The effects of the two groups of oral agents on insulin receptors were studied in several types of cells in tissue culture: MCF-7 human breast cancer cells, IM-9 human lymphocytes, human fibroblasts, and H-35 rat hepatoma cells. In none of these cells did the four sulfonylureas tested, tolbutamide, glibenclamide (glyburide), gliclazide, and glisolamide, have any significant effects on insulin binding to its receptor. In contrast the two biguanides tested, phenformin and metformin, increased insulin binding in all cell types by 44 to 101%. These studies raise the possibility, therefore, that biguanides may have a direct effect on insulin receptors and this effect may account for the known effects of biguanides to lower elevated blood sugar levels in diabetic patients.

Biguanides↗