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Biomedical subjects

V T Rendano

Publications and source records attributed to V T Rendano.

At least 37 records · Page 2Linked to original sources

Equine verminous arteritis; efficiency and speed of larvicidal acitivty as influenced by dosage of albendazole.

Albendazole was effective in destroying Strongylus vulgaris larvae in verminous lesions of the cranial mesenteric artery when administered as a 20% suspension by stomach tube to ponies. Fifty mg/kg body weight administered twice a day for 2 days caused death and gradual disintegration of larvae over a period of 3 to 6 weeks with mild toxic signs appearing in 3 of 11 ponies. Higher total doses of albendazole (50 mg/kg twice a day for 4 days and 25 mg/kg three times a day for 5 days) lead to more rapid disintegration of the larvae but fatal toxicity was observed in 3 of 6 ponies so treated. In all cases, resolution of verminous arterial lesions was delayed until larva remains had disappeared from the lesions. A non-parametric analysis was applied to combined radiographic, pathologic and parasitologic observations and data for testing their statistical significance

Administration, Oral↗

Equine verminous arteritis. An arteriographic evaluation of the larvicidal activity of albendazole.

Albendazole was an effective larvicidal anthelmintic against the fourth stage Strongylus vulgaris larvae as late as one month post-infection. The drug was administered at a dose rate of 25 mg/kg three times daily for 5 days. Diarrhoea occurred in 3 of 4 foals treated and of these one died during belated intravenous therapy for dehydration. Arteriography allowed for an in vivo assessment of the development and regression of lesions in infected-treated foals compared to the continued development of lesions in infected-untreated foals. The arteriographic findings were confirmed at necropsy.

Albendazole↗

The equine teeth.

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Alveolar Process↗