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Biomedical subjects

V Smith

Publications and source records attributed to V Smith.

At least 145 records · Page 8Linked to original sources

Dynamics of contraceptive failures.

The purpose of this study was to explore the vicissitudes of contraceptive efforts and practice, and human behavior contributing to contraceptive failure. A consecutive sample of 481 women, who visited various gynecological out-patient clinics of a New York City municipal hospital between August 1974 and August 1975, served as the study population. There were 181 women with planned pregnancies and 300 women with unplanned pregnancies. The data were gathered in personal interviews. By comparison of both groups it was discovered that the women with unplanned pregnancies, because of their lower frustration tolerance level, had been led by successive difficulties related to contraceptive efforts and practice to episodic, faulty, or nonuse of technically effective contraceptive methods. Thereafter, psychological processes and mechanisms gave rise to a false sense of security, which virtually prevented them from resuming contraceptive practice. These psychological processes and mechanisms also govern other spheres of human behavior and merit systematic investigation.

Adult↗

A rapid and sensitive method for determination of theophylline in plasma and saliva by high pressure liquid chromatography.

A fast and sensitive high pressure liquid chromatographic method for the monitoring of theophylline concentrations in plasma or saliva was developed. Each sample requires only about 15 minutes for the completion of the assay after receiving the plasma or saliva sample. Only 0.1 ml of sample is required, and concentrations as low as 1 mcg/ml can be accurately measured.

Caffeine↗

Tumor and normal tissue response to irradiation in vivo: variation with decreasing dose rates.

Continuous irradiation in vivo at dose rates ranging form 0.54 to 274 rads per minute was performed in mice using the EMT6 tumor, the gut clone system, and the bone-marrow CFU system. A progressive increase in D0 and decrease in ñ were seen with decreasing dose rates in the EMT6 tumor and the gut clone system. The D0 showed little change in the bone-marrow CFU system. These findings are related to the D2-D1 values obtained from split-dose experiments at conventional dose rates. The results do not fit the various mathematical models proposed for correlating the effects of continuous low-dose-rate irradiation and acute exposure.

Animals↗