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Biomedical subjects

V Skoda

Publications and source records attributed to V Skoda.

At least 37 records · Page 2Linked to original sources
PubMed1977

Alkaline phosphatase activity in relation to LDH5 (L-lactate: NAD+ - oxidoreductase, E.C.1.1.1.27) in patients with precancerous conditions of the endometrium.

We investigated the serum activity of the fifth fraction of L-lactate: NAD-oxidoreductase (E.C.1.1.1.27) and serum alkaline phosphatase activity prior to diagnostic curettage in patients with abnormal and atypical endomertial hyperplasia. We also determined them in 75 patients with carcinoma of the endometrium, 80 patients with glandular cystic endometrial hyperplasia and a "normal" control group of 70 patients. In the statistical evaluation we found a significantly high incidence of low AP activity and elevated LDH5 in the group of patients with glandular cystic endometrial hyperplasia, as well as in patients with precancerous lesions of the endometrium and carcinoma of the endometrium. The findings raise the question of whether these changes in the serum activity of the given enzymes are only a response to a given hormonal modulation.

Alkaline Phosphatase↗
PubMed1975

[Determination of the nucleolar coefficient in lymphocytes in chemotherapeutically treated patients with ovarian carcinoma].

At the total evaluation of the base values of lymphocytes in the patients with Ca ovariorum a lower number of lymphocytes was found than in the healthy population. At the same time the lymphocytes in the patients with Ca contained a lower number of nucleoli which are capable of the synthesis RNA (i.e. nucleoli ringsingers and active) and a higher number of nucleoli irreversible unable of the synthesis of RNA, i.c. micronucleoli. So the value of the nucleolar coefficient was rised, too, in these patients. It seems, that the described changes were dependent of the clinic condition of our patients, in some cases they preceded the state. This method is utilised at the IInd Obstetric Gynaec. Clin. in Prague for the long time cytostatic therapy.

Acrylates↗