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Biomedical subjects

V S Vasil'ev

Publications and source records attributed to V S Vasil'ev.

At least 19 recordsLinked to original sources
PubMed2003

[Integral mathematical parameters of a gemogram as criteria for evaluation of severity of chronic adnexitis and of treatment efficacy in conservative therapy].

A number of hematological indices of the peripheral blood in patients with chronic adnexitis were mathematically calculated to evaluate a disease severity and an effect of recovery by using the traditional therapy method. It was established that the integral-and-mathematical indices of hemogram reflect clinical disease acuteness while receiving patients to hospital. A comprehensive evaluation of hematological indices makes it possible to determine the severity of inflammatory process in women, to detect the efficacy of a conducted therapy and to choose a strategy for further metabolic correction to ensure a maximum treatment effect.

Anti-Infective Agents↗
PubMed1994

[Differential diagnosis of and diphtheria and tonsillitis].

Differential diagnostic differences have been analyzed for faucial diphtheria (41 patients), infectious mononucleosis (219 patients), follicular and lacunar tonsillitis (71 patients), Vincent tonsillitis (22 patients). Besides specific clinical manifestations, of special importance in distinguishing the above diseases was a profound analysis of hemogram with calculations of special parameters and variants of ESR/leukocyte count ratio.

Adult↗
PubMed1992

[Comparative effectiveness of various antibiotics in the treatment of patients with meningococcal meningitis].

The results of treating 322 patients with various forms of meningococcal infection accepted to a hospital within a year are presented. The patients were divided into 3 groups by the character of etiotropic therapy. The patients of group I were treated with benzylpenicillin and those of group 2 were treated with levomycetin sodium succinate. Group 3 included the patients, the therapy of whom with the above two antibiotics failed and they were subjected to treatment with cefazolin, cefotaxime, amikacin and other broad spectrum antibiotics. Benzylpenicillin generally proved to be the drug of choice in the antibacterial therapy of meningococcal infection. In comparison to levomycetin (chloramphenicol) it provide more rapid clinical recovery of the patients and normalization of the indices of the cerebrospinal fluid. Only failure of benzylpenicillin therapy was considered as an indication to the broad-spectrum antibiotics to be in the complex treatment of the patients. As additional methods for estimating the efficacy of antibacterial therapy it was recommended to employ calculation of the integral indices of hemograms (the leukocyte index of intoxication and the hematologic index of intoxication).

Adolescent↗
PubMed1992

[Lipid peroxidation and composition of the erythrocyte membranes in patients with viral hepatitis B].

A study is presented of lipid peroxidation and composition of lipids in erythrocyte membranes in 39 patients with viral hepatitis B. It was established that the content of free cholesterol, lyzophosphatidylcholins, malonic dialdehyde, lipohydroperoxides showed an increase while the level of phospholipids and antioxidant activity decreased in all patients. In patients with viral hepatitis B cytolytic syndrome the content of phosphatidylcholins and sphingomyelins was reduced while in those with cholestasis syndrome the content of phosphatidylethanolamines was reduced.

Adolescent↗
PubMed1992

[The use of water-soluble vitamins in viral hepatitis A].

To correct disbolism of vitamins C, B3, B6 and B12 due to viral hepatitis A (VHA), the patients received daily doses of the vitamins: 300 and 400 mg of ascorbic acid, 300 and 600 mg of calcium pantothenate or 90 and 180 mg of pantetin per os. 100 and 200 micrograms of cyanocobalamin alternating with 50 and 100 mg of pyridoxin was given intramuscularly every other day. The course lasted 3-4 weeks. The vitamin treatment promoted a positive trend in clinico-biochemical parameters, normalization of immunocompetent cell and serum immunoglobulins levels, of phagocytic reaction of peripheral blood neutrophils.

Antibody Formation↗
PubMed1990

[Use of trental in combined treatment of viral hepatitis].

The effectiveness of trental administration was investigated in 94 patients aged 18-65 suffering from hepatitis A or B running a moderate course. The data were analyzed for clinical features, blood red cell diene conjugates and ATPase activity, malonic dialdehyde production, plasma alcohol dehydrogenase. Administration of trental produced a positive action on lipid peroxidation, liver size, jaundice duration. Hospital stay of the patients reduced. Basing on the above observations, the authors advocate wider introduction of trental in management of virus hepatitides.

Adolescent↗
PubMed1989

[Humoral and cellular indices of nonspecific resistance in viral hepatitis A and ascorbic acid].

A total of 260 patients aged 15 to 57 years with virus hepatitis A were examined over time for some indicators of humoral and cellular immunity (serum IgA, IgM, IgG, the phagocytic number and indicator of the completeness of neutrophil phagocytosis, cytochemical content of ribonucleic and deoxyribonucleic acids in blood leukocytes). The immunological indicators were determined in two patients' groups after intake per os of 300 mg/day of ascorbic acid for 2-3 weeks and without its administration. It has been established that in virus hepatitis A, vitamin C exerts a remarkable immunomodulating action. In view of this fact, it should be necessarily included into multimodality treatment of patients suffering from pathology under consideration.

Adjuvants, Immunologic↗
PubMed1984

[Possibilities for cytochemical research on neutrophils and lymphocytes in assessing the severity of the course and the completeness of recovery in viral hepatitis B].

Some cytochemical characteristics were determined in peripheral blood lymphocytes and neutrophils of patients with HBsAg-positive hepatitis. The reduction of phospholipids, lysosomal cation proteins, neutrophil peroxidase and lymphocyte succinate dehydrogenase was found to correlate with the disease severity. Acid phosphatase activity and the content of lymphocyte RNA were discovered to increase depending on the disease severity. Complete recovery of the characteristics enumerated occurred only in mild forms of hepatitis.

Hepatitis B↗