Biomedical subjects
Publications and source records attributed to V S Pogosov.
Hearing disorders are characterized for citizens of the East Siberia belonging to Europeoid or Mongoloid race. Interpopulation features of hypoacusis of various genesis and effects of natural-geographic and ethnic factors on hypoacusis manifestations in native Mongoloid and migrant Europeoid Siberian population are shown.
The article presents classification of mixed forms of hypoacusis based on certain combination of audiological criteria reflecting the impact of a hypoacusis neurosensory component. A differential approach to rehabilitation of patients with mixed hypoacusis caused by chronic pathological processes in the middle ear is proposed. The approach allows for severity of neurosensory hearing disorders.
The authors propose a method of endoural ultrasound therapy in parallel with local introduction of ozonized physiological solution for patients with otitis media purulenta chronica. Locally used was the solution containing ozone in concentration 10 mg/l. Low-frequency ultrasound therapy was conducted using Tonsillor-2 unit with special intraauricular wave guides. Treatment outcomes in 132 patients are analysed for 5 years. The response was registered in the majority of cases.
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Experimental and clinical trials have shown that anesthesia and intensive therapy of shock incorporating tranexamic acid enhance analgesia, hyporeflexia, thus ensuring stable, adequate anesthesia which is safe under reduced doses of standard anesthesiological modalities. Application of tranexamic acid provided more favourable course of postanesthesiological and postoperative periods, decreased the number of complications and lethal outcomes compared to standard anesthesia.
A novel radiosurgical method of cutting tissues and coagulation of ENT operations is presented. Indications, technique, device operation regimes are provided. Radiosurgery has evident advantages: saving cut with minimal damage to the adjacent tissues, good coagulating effect warranting "dry field" for the surgeon, absence of necrosis of the wound walls, fast healing, simple operative procedure. Radiosurgery holds great promise for otorhinolaryngological practice.
227 young men and boys aged 9-22 years underwent treatment for juvenile angiofibroma of the base of the skull (JAFBS) in the ENT clinic of the Russian Academy of the Advanced Medical Education between 1977 and 1998. JAFBS was most frequently diagnosed at the age 15-18 years. An original clinicotopographic JAFBS classification is proposed basing on the disease spread. A complex of tests has established that JAFBS patients develop changes in hormonal and immunological statuses. Indications to ligation of the external carotid arteries and a modified nasomaxillary approach to angiofibroma providing radical removal of the tumor are described. After surgical treatment only 11.5% of the patients exhibited recurrent tumors.
Historical evolution of frontal sinus trepanopuncture with description of its benefits and shortcomings is presented. The perfection of the method lies in introduction of technological innovations raising safety of the procedure and provision of the approach sufficient for modern therapeutic and diagnostic techniques.
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Optimal methods of endotracheal anesthesia using non-opiate drugs of four classes (clofelin, transamine, contrykal, ketanes) have been fundamentally grounded developed and tried in extensive and traumatic operations for ENT malignant and vascular tumors as well as inflammation in patients of high anesthesiological operative risk. The drugs were used in 174 patients including 13 children. 87.9% of the patients had concomitant diseases: blood hypertension, coronary heart disease, chronic nonspecific pulmonary diseases, bronchial asthma, asthmatic bronchitis, diabetes mellitus, anemia. Adequate stable anesthesia was achieved in reduced dosage of conventional anesthesiological agents.
Ninety six patients with chronic epitympanitis treated surgically were examined immunologically and allocated in 4 groups. Suppressed T- and B-cell immunities were found. Patients of group 1 received antibiotics and antihistamine drugs (controls), patients of group 2, 3 and 4 were given in addition timontin, myelopid and timontin + myelopid, respectively. Monotherapy with timontin and myelopid improved immunological status of the patients who exhibited better outcomes of conventional treatment than controls. Combined use of the above immunomodulators corrected the immunological defects and resulted in good clinical response.
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Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.