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Biomedical subjects

V S Karpenko

Publications and source records attributed to V S Karpenko.

At least 19 recordsLinked to original sources

[Effectiveness of treatment of urethral traumatic stricture complicated with prostatitis and vesiculitis].

A system for the assessment of the results of the operative treatment of a traumatic stricture of the urethral canal is suggested. Of the 63 patients operated on, a long-term results was studied in 39 (62%). The radical operation of Karpenko, Kholtsov, Rusakov have proved to be the most effective. Maximum effectiveness of the operative treatment was noted in diseases duration of up to 1 year. A new concept of pathogenesis of the complications which occur in patients with recurrent traumatic stricture of the urethral canal has been developed.

Follow-Up Studies

[Rehabilitation of sexual function in patients with traumatic urethral injuries].

The complex urologic and sexologic examination of the urethral canal was performed in 56 sufferers with urethral trauma. By means of cavernosography, the ways of the venous blood chrowing from the cavernous bodies were established. Pathogenesis of impotence is considered. The recommendations on rehabilitation, prophylaxis of the disorder in sexual function in patients with traumatic stricture of the urethral canal are given. It is shown that endofallografting is the most effective and pathogenetically substantiated method for the treatment of impotence in sufferers with traumatic injury to the urethral canal.

Adult

[Diagnosis and treatment of complicated and recurrent traumatic strictures of the urethral canal].

In 40 patients, the treatment for traumatic stricture of the urethra lasted 3 and more years. In complex examination, the short urethral stricture was revealed in 10, long one--in 30 patients. Stricture of the membraniform portion of the urethra was diagnosed in 28, prostatic one--in 10, spongiform one--in 2 patients; changes in the prostate and seminal vesicles were revealed in 36. At operation, the scars of the narrowed urethra were excised en-block with the cicatricially changed prostate up to the neck of the urinary bladder, it was anastomosed to the unchanged portion of the urethra. Drainage was accomplished via the urethra by means of the Foley catheter and suprapubic drain. In all the patients, the independent uresis was restored.

Humans

[The function of the internal carotid artery in patients with vascular optic neuropathies].

Roentgenographic and angiographic examinations of 140 patients with vascular optic neuropathies have revealed atherosclerotic changes of internal carotid artery in 66.4% and 94.6%, respectively. Stenosis of internal carotid artery was recorded in 85.7%, thrombosis--in 8.9% of cases. In 55.9%, ostium stenosis of internal carotid artery is associated with its pathologic winding and is one of causes of acute disturbances in blood circulation in the optic nerve. Atherosclerotic changes of internal carotid artery are recorded in its extracranial segment in 69.6% of cases.

Adult

[The morphological changes in the seminal vesicles in prostatic sclerosis].

A study is presented of morphological changes of the seminal vesicles removed during prostatectomy in 51 patients with sclerosis of the prostate and histological findings of the seminal vesicles were compared with roentgenological signs on the vesiculograms and clinical manifestations of the disease. Results indicate that the seminal vesicles undergo significant pathological changes in the development of sclerosis of the seminal vesicles requiring in some cases their surgical removal for restoration of the urodynamics in cystic-urethral segment.

Adult

[Radionuclide assessment of urodynamics and kidney function in prostatic sclerosis patients (before and after surgery)].

A study was made of 137 patients with prostatic sclerosis ranging in age from 14 to 79. Basing on the results of clinical, x-ray and radionuclide examination of patients with prostatic sclerosis 3 degrees of disturbed urodynamics of the lower urinary tract have been singled out for this disease entity: compensated, subcompensated and decompensated. In accordance with the above degrees of the disturbed urodynamics groups of patients have been analysed before and after surgery (partial and subtotal resection of the prostate and prostatectomy). Prostatic sclerosis has been shown to cause changes in the urine output rate, the time of urination and residual urine. The UFM index is lowered as compared to the normal one more than 6 times. Residual urine (RU) reached 234.0 +/- 62.2 ml, the time of urination is extended by more than 2.4 times. It has been established that disturbed permeability of the posterior urethra results in the disturbance of the urodynamics of the upper urinary tract, separate and summary renal function. Radionuclide investigation helped to study the long-term results of operation efficacy by the reparation of the urodynamics in 91 patients with prostatic sclerosis. In most of the patients, the urodynamic indices returned to normal or improved: in 78.2% of the patients with prostatic sclerosis, the time of urination returned to normal, in 21.2% the time reduced. The UFM index returned to normal in 36.2% of the patients, in 40.6% it was moderately reduced, and in 23.0%, it remained sharply reduced. RU over 100 ml was determined in 6.5% of the patients only. After reparation of the permeability of the posterior urethra renal function either returned to normal or greatly improved in 37.9% of the patients. In 52.5% of the patients, renal function did not reach normal however, gradually improving it got stable at a certain level which was sufficient for the improved conditions of a patient and his future life.

Adolescent