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Biomedical subjects

V S Antonov

Publications and source records attributed to V S Antonov.

At least 19 recordsLinked to original sources
PubMed1997

[The difficulties of clinical diagnosis of mixed-infection of tick-born encephalitis and Lyme disease].

The authors report 49 cases of mixed infection (Lyme disease + tick-born encephalitis). All the patients were citizens of the Russian North-West. Clinically, there were symptoms of Lyme disease (erythema) and tick-born encephalitis (serous meningitis, neuritides of the cranial and peripheral nerves). In patients with mixed infection in the presence of erythema symptoms of tick-born encephalitis were less evident. The diagnosis of Lyme disease erythema-free form in combination with tick-born encephalitis may be made only by dynamic serological tests for both of these infections.

Aged↗
PubMed1992

[Experience with the use of an immunoglobulin erythrocyte preparation for the early laboratory diagnosis of pseudotuberculosis].

An immunoglobulin erythrocytic preparation for the rapid detection of Yersinia pseudotuberculosis was developed. The preparation was shown to be specific and sufficiently sensitive (8 x 10(5) microbial cells/ml). The preparation was used for the examination of 102 patients; in 62 of these patients the diagnosis was confirmed by means of common laboratory and clinical methods. Y. pseudotuberculosis antigen was detected in the blood of 39 patients (63%), and in 12 patients (29.4%) the results of traditional laboratory tests were negative. In 19 out of 23 patients the coincidence of the results of bacteriological and seroindication study was registered. During the study of the remaining 40 patients the antigen was detected only in 6 patients, including 3 patients with enteric yersiniosis.

Antigens, Bacterial↗
PubMed1991

[Early clinical and laboratory diagnosis of pseudotuberculosis].

As shown by the examination of 188 patients with suspected pseudotuberculosis, the latter produces a greater total of clinical manifestations than any other nosological entities differentiated from it. Conventional (retrospective) techniques of laboratory diagnosis (bacteriological ones, indirect hemagglutination) confirmed the diagnosis in 76.1% of the cases against 93.1% under new rapid techniques of seroindication (enzyme immunoassay and antibody neutralization). Moreover, the diagnosis with new techniques can be managed earlier. The overall assessment of clinical symptoms and techniques of seroindication allow early administration of valid treatment thus avoiding recurrences and complications of pseudotuberculosis.

Humans↗
PubMed1990

[An automated method of detecting bacteriuria].

A screening test for bacteriuria was developed, based on the use of the Bioscreen microbiological system (Labsystem, Finland) and nutrient media manufactured in the USSR. The diagnostic characteristics of the new test were assessed in screening of inpatients; the test has proved to be not inferior to similar methods realized in the microbiological systems manufactured in Western Europe and USA.

Bacteriological Techniques↗
PubMed1990

[Diagnosis of hemorrhagic fever with renal syndrome].

The authors observed 22 patients with hemorrhagic fever with the renal syndrome (HFRS). The diagnosis turned out to be difficult in outpatient clinics as all the patients were referred to hospital with erroneous diagnoses. Epidemiological causes of infection of HFRS were indicated. The authors singled out 3 periods in a course of this disease with characteristic symptoms. The diagnosis was confirmed serologically in the reaction of indirect immunofluorescence, a 4-fold increase and over in antibody titer was observed. A case history was presented.

Adolescent↗
PubMed1989

[Metrological requirements for clinical laboratory studies].

The paper analyzes the foreign literature on the achievements and tendencies in the unification of measurements of physicochemical characteristics of biologic materials at laboratories for clinical diagnosis. Reviews the principles of creating a reference basis and an hierarchic system of measuring, reference, and working methods and devices, that should provide a transfer of the measured values from the reference values to working means of measurements. Discusses the contribution of the reference materials to the system of measurements of the biosample composition. Presents data on the standard reference material of the USA National Bureau of Standards for clinico-diagnostic laboratory studies.

Government Agencies↗