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V Ramakrishnan

Publications and source records attributed to V Ramakrishnan.

184 records · Page 11Linked to original sources

Structures of prokaryotic ribosomal proteins: implications for RNA binding and evolution.

After a long hiatus, the pace of determination of the structures of ribosomal proteins has accelerated dramatically. We discuss here the structures of five ribosomal proteins from Bacillus stearothermophilus: S5, S17, L6, L9, and L14. These structures represent several new motifs. Each of these structures has revealed new insights, and we have developed criteria for recognizing RNA-binding regions of each protein and correlating the structures with such properties as antibiotic resistance. The information here should also prove invaluable in an eventual high-resolution picture of the intact ribosome.

Bacterial Proteins↗