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Biomedical subjects

V R Lala

Publications and source records attributed to V R Lala.

8 recordsLinked to original sources
PubMed1998

Combined cervical and intraoral approach to lingual thyroid: a case report.

BACKGROUND: Lingual thyroid is a rare anomaly that may require surgical intervention. Lesions have been approached either via the neck or transorally. Advantages and limitations exist with each technique. METHODS: A 10-year-old female on long-term suppression therapy for lingual thyroid developed progressive dysphagia; surgical excision was performed. Suprahyoid pharyngotomy was used to dissect the posterior limits of the tumor. Resection was completed via a transoral approach. RESULTS: Cervical exposure allowed safe access to the posterior tumor margins. Transoral exposure permitted direct dissection of the anterior margin of the lesion, rendering complete excision simple. CONCLUSION: A combined surgical approach to lingual thyroid is a safe technique that affords excellent visualization and facilitates resection.

Anti-Bacterial Agents↗
PubMed1988

Prolactin and thyroid status in prepubertal children with mild to moderate obesity.

Prolactin (PRL) response to thyrotropin releasing hormone (TRH) in 21 prepubertal children with mild to moderate obesity was compared with that in 21 normal prepubertal children (controls). Basal PRL levels were normal but the mean peak PRL response and mean increment in PRL levels following TRH administration were significantly lower in prepubertal obese children (p less than 0.001). The mean PRL responses to TRH were significantly impaired at all time intervals in prepubertal obese boys and girls compared to the control subjects. Linear regression and correlation coefficient analysis did not reveal any significant relation between the percent overweight and PRL response. Basal T4, T3 levels and T3 and TSH response to TRH were similar in both groups. The findings suggest that neuroendocrine regulation of prolactin is impaired in prepubertal children even with mild to moderate obesity. This could be secondary to altered neurotransmitter status at the hypothalamic level. Further studies are needed to determine whether the defect is innate or acquired, primary or secondary.

Child↗
PubMed1984

Breaker's neck.

Explore the source record for details and available documents.

Adolescent↗
PubMed1979

Glucagon suppression with low-dose intramuscular insulin therapy in diabetic ketoacidosis.

The effects of low-dose intramuscular insulin therapy on endogenous glucagon secretion in diabetic ketoacidosis were compared prospectively with a conventional regimen. Ten patients, 4 to 15 years of age, who had 13 episodes of diabetic ketoacidosis, were alternately assigned to either group. Either 0.1 unit/kg regular insulin was given every two hours im, or 1.0 unit/kg regular insulin was given, half subcutaneously and half intravenously, every 4 hours. In both groups, a significant and equal fall in both serum glucose and glucagon concentrations was observed. No complications were encountered. It is concluded that 0.1 unit/kg of regular insulin given im every two hours is as effective in correcting hyperglycemia and hyperglucagonemia of diabetic ketoacidosis as is conventional therapy, and avoids the risks of secondary hypoglycemia known to occur when the larger insulin dosages are employed.

Blood Glucose↗
PubMedDate not supplied

Hypoglycemic hemiplegia in an adolescent with insulin-dependent diabetes mellitus: a case report and a review of the literature.

A case of hypoglycemic hemiparesis in a fifteen-year-old girl with insulin dependent diabetes mellitus (IDDM) is described. The initial presentation included left facial paresis and muscular weakness of the left upper and lower extremities, associated with a blood glucose level of 31 mg/dL. The patient recovered completely after a glucose infusion. Her neurological examination became normal within 24 hours and remained so for a follow-up period of 6 months. Hypoglycemic hemiparesis is rarely described in children and adolescents.

Adolescent↗