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Biomedical subjects

V R Joshi

Publications and source records attributed to V R Joshi.

At least 127 records · Page 7Linked to original sources

Comparative evaluation of antipyretic activity of ibuprofen and aspirin in children with pyrexia of varied aetiology.

The antipyretic activity of ibuprofen and aspirin was compared in sixteen children with pyrexia due to upper respiratory tract infection and in twelve with fever due to other causes. All 28 children received ibuprofen (7 mg/kg of body-weight) and aspirin (15 mg/kg of body-weight) in a single dose on 2 consecutive days in a crossover manner. Rectal temperature was recorded prior to and at regular intervals up to 8 hours after drug administration. Analysis of the results indicate that ibuprofen and aspirin effectively lower temperature and the two drugs are comparable in their antipyretic activity. In conclusion, significant antipyretic activity, good tolerance profile and availability in syrup form make ibuprofen a useful substitute for aspirin in children with fever.

Aspirin↗

Lymphatic varices in blocked fistulous rheumatism.

Blockage of a chronic synovial fistula over the right elbow in a man with erosive, nodular rheumatoid arthritis is described. A subsequent synoviogram demonstrated gross lymphatic hypertrophy draining the joint. The implications of this finding are discussed.

Aged↗