The authors analyse the frequency, the significance for prognosis and the localisation of the neuropsychological manifestation concerning the steps of evolution of the HIV infection in children. The pathogenetic aspects, the principal histopathological lesions and clinical corresponding aspects are also presented. The text refers to the modern neuroimaging investigations and to the new treatment possibilities.

AIDS Dementia Complex↗

PubMedDate not supplied

[The indications for intravenous immunoglobulins in pediatric practice].

Current techniques allow the manufacture of intravenous immunoglobulin that fully retain their antibody content and function. Immunoglobulins have been show to be effective therapy for immune thrombocytopenia, neonatal allo(iso)immune thrombocytopenia, agammaglobulinemia, acquired immunodeficiency., premature neonates, burn patients, prophylaxis and treatment of infection in high risk and other conditions.

Adjuvants, Immunologic↗

PubMedDate not supplied

[Antiviral chemotherapy in pediatrics--its present and prospects].

Authors discuss the general aspects of viral infections and the principles of antiviral chemotherapy. First section deals with the stages, the types of viral infections and the basic principles for action of antiviral drugs. Authors review also the up-to-date situation of antiviral therapy in pediatrics, the problem of resistant strains and formulate the expected progress in the field of antiviral chemotherapy.

Antiviral Agents↗

PubMedDate not supplied

[The diagnostic algorithm in neonatal infections].

Authors review the principles of diagnosis in neonatal bacterial infections (local and systemic), in congenital, peri- and postnatal viral infections and also in Candida spp. and other mycotic infections of the neonatal period. They try to delineate the clinical and epidemiological criteria of suspicion and modalities of confirmation of the neonatal infections by specific paraclinical methods. Attention is focused on modern diagnostic methods (such as immunofluorescent techniques, counterimmunoelectrophoresis and so on), which are important for the early etiological diagnosis and for thr rapid initiation of specific therapy. Authors made a practical diagnostic algorithm for the most frequent encountered neonatal infections. They also focused on the recent changes in the etiology of neonatal infections and their therapeutic significance.

Algorithms↗

PubMedDate not supplied

[A diagnostic algorithm--coma].

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Algorithms↗

PubMedDate not supplied

[Pathogenetic mechanisms in neonatal infections].

The authors reviewed the pathogenetic mechanisms of ante-, intra- and postnatal infections of the newborn. They also discussed the results of the antenatal infections on embryo and foetus, and the clinical variants of intra- and postnatal infections. The attention is focused on the relationship between pathogenetic mechanisms and the relevant clinical and paraclinical alterations for the diagnosis of the most frequent encountered infections of the newborn.

Communicable Diseases↗

PubMedDate not supplied

[The respiratory manifestations of the acquired immunodeficiency syndrome in children].

The authors present the pulmonary complications (infectious and non infectious) in children with AIDS. It is shown that in this group of children the pulmonary complications are the first cause of death, and among them, the most frequent are the interstitial lymphoid pneumonia and Pneumocystis carinii pneumonia.

AIDS-Related Opportunistic Infections↗

PubMedDate not supplied

[A diagnostic algorithm--hepatomegaly].

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Algorithms↗