[Complicated forms of cancer of the large intestine].
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Biomedical subjects
Publications and source records attributed to V P Zinevich.
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A technique of closing colostomy and reestablishing the continuity after its resection is described. Good long-term results were obtained in 102 of 104 patients.
The article presents an analysis of dynamics of changes of serum cholinesterase activity in patients with peritonitis resulting from the effect of UVI blood. It was established that it resulted in more rapid recovery of the functional activity of hepatocytes. A serial investigation of fluctuations of the serum cholinesterase activity may serve a criterion for the assessment of prognosis of the disease.
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Based on an analysis of lethal outcomes in 20 of 326 patients with perforated ulcers of the stomach and duodenum the authors recommend to perform planned operations more often in elderly and senile patients, to combine suturing the ulcer with truncal vagotomy, intensive therapy, administration of drugs, catheterization of the superior mesenterial artery.
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The article analyzes the development of viewpoints to pathogenesis of acute intestinal obstruction and modern principles of treatment of the disease.
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Great diagnostic value of the method of primary double contrast of the large bowel under conditions of its artificial hypotonia was shown on the basis of the examination of 30 patients with acute impassability of the large bowel.
One of important components of endogenous intoxication in acute pancreatitis is considered to be middle-mass molecules possessing high toxicity. Hemosorption improves results of complex therapy and reduces postoperative lethality by 10% at an average. The positive effect of hemosorption in focal pancreanecrosis is associated with sorption of lipase, trypsin, middle-mass molecules and other metabolites. In total pancreanecroses the effect of hemosorption was minimal. In hemosorption on the sorbent SKN the oxygenation and regional heparinization of the sorbent is indicated.
The article presents results of treatment of 300 patients with acute cholecystitis, 285 of them (95%) being operated upon. Hepatic insufficiency was found to develop in 173 patients (57,6%). The operation of choice was cholecystectomy (97,1%). Cholecystostomy was fulfilled in 7 patients (2,4%), in 2 patients (0,5%) choledocholithotomy was made following a previous cholecystectomy. Lethality in patients with hepatic insufficiency was 4 times as high as in patients without it. In 34,1% of the operated patients hepatic insufficiency was the main cause of death.
During the recent years 202 patients with cholelithic disease and its complications have been treated in the clinic. In 135 patients admitted to the hospital an attack of severe pains was followed by jaundice and symptoms of hepatic insufficiency (HI). A compensated stage of HI was diagnosed in 68 (50.4%) patients, subcompensated stage--in 38 (28.1%), decompensated--in 25 (18.5%) and terminal stage of HI--in 4 patients (3%). The operative treatment was used in 142 patients (70.3%). The operation of choice was cholecystectomy. An intervention on the common bile duct was performed in 59 patients (41.5%). Operations were performed on 42 patients with the compensated stage of HI (one of them died), in 17 patients with the subcompensated stage (one patient died), in 16 patients with the decompensated stage (three patients died); with the terminal stage there were 4 patients operated upon. Two of them died.
The article presents data concerning the surgeons who worked at the Leningrad Medical Institute for Postgraduate Training and achievements of surgical departments during 100 years of existence of the institute.
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