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Biomedical subjects

V P Sood

Publications and source records attributed to V P Sood.

At least 19 recordsLinked to original sources
PubMed1993

Small round virus excretion in long-stay geriatric patients.

The role of small round viruses (SRVs) in gastroenteritis has not been evaluated. We undertook a study to evaluate SRV excretion in 40 elderly patients over 12 months in long-stay, geriatric wards. The 40 patients (11 male, 29 female) had an age range of 73-99 years. Samples were received monthly as long as the patients were alive. Samples were available from 30 patients (75%) for 6 months or more, and 20 (50%) patients completed the study. Ten grams of faeces were collected and prepared as 10-20% suspensions, and then concentrated and examined by electron microscopy. Of 348 samples examined, 116 (33%) contained SRVs. Only 5 of 40 patients did not excrete virus. However, in 103/116 (89%) positive samples, virus was present in small amounts. These results show that excretion of SRVs in asymptomatic patients was very common. Therefore, the detection of SRVs in small amounts during an outbreak of gastroenteritis suggest that they do not have a causal role.

Aged↗
PubMed1990

Height and weight of 'well-to-do' school children in Haryana.

A study was conducted in five public schools of Haryana. Height and weight of 4405 well-to-do school children (both sexes) between the ages of 5 to 15 years were measured using standard accepted technique. Height and weight of children were compared with the Indian Council of Medical Research (ICMR) standards; the values of mean height and weight of the Haryana children were significantly higher for both sexes at all ages.

Adolescent↗
PubMed1990

Skinfold thickness in well-nourished school children in Haryana.

Skin fold thickness of 4405 (2212 male and 2193 female) well-nourished school children between 5 to 15 years of age in five public schools of Haryana was measured by standard accepted technique. The findings of the present study were comparable with earlier studies conducted in well-nourished Indian school children at Hyderabad and with the British children. Children belonging to low income groups had smaller fat folds at all ages as compared to the present study.

Adolescent↗
PubMed1986

Indoramin in the hypertensive diabetic patient.

In 32 hypertensive diabetic patients a study was performed to determine the effects of indoramin on blood pressure and blood glucose, plasma insulin, C-peptide, serum total cholesterol, and triglyceride levels. All patients evaluated showed a significant fall in blood pressure with daily doses of 50 to 200 mg of indoramin. In six insulin-dependent diabetic patients there was no change in diabetic control and no effect on the incidence of hypoglycaemia. In 18 noninsulin-dependent diabetics monitored for 3 months and in 14 followed for 12 months, there was no significant change in glucose tolerance after a 75 g glucose dose; mean plasma C-peptide levels and 2 h insulin levels were increased at 12 months. Mean weight and mean fasting cholesterol and triglyceride concentrations were unchanged. Nine patients withdrew because of side effects, mainly drowsiness and lethargy.

Adolescent↗
PubMed1982

Response of the renin-angiotensin-aldosterone system to upright tilting and to intravenous frusemide: effect of prior metoprolol and propranolol.

1 Upright tilting in normal volunteers caused increases in plasma active and total renin, angiotensin II and aldosterone; a slight but significant fall in inactive renin accompanied these changes. 2 The alterations in the renin-angiotensin-aldosterone system on tilting took up to 1 h upright to become fully established. 3 Large intravenous doses of propranolol or metoprolol attenuated, without abolishing, the rises in active renin, angiotensin II, and aldosterone; the attenuation was most evident soon after tilting and was largely overcome by 1 h upright. Inactive renin did not fall significantly after beta-adrenoceptor blockade. 4 Intravenous frusemide caused immediate rises in plasma active, total and inactive renin, angiotensin II, and aldosterone, which then declined over 2 h despite increasing cumulative sodium losses. 5 Intravenous propranolol or metoprolol attenuated, without abolishing, these early increases in the components of the renin-angiotensin-aldosterone system after frusemide. 6 Prior oral metoprolol or propranolol, while significantly slowing the heart, did not limit the early rise in plasma angiotensin II following intravenous frusemide. 7 Thus in contrast to previous workers, we did not find that propranolol eliminated the response of the renin-angiotensin system to upright tilting; in part this difference appeared to be due to the longer tilt we employed. 8 Also in contrast to earlier work, we found attenuation by both intravenous propranolol and metoprolol of the immediate rise in renin after intravenous frusemide.

Adrenergic beta-Antagonists↗
PubMed1981

The effect of oral prazosin on blood pressure and plasma concentrations of renin and angiotensin II in man.

1. We studied the effect of oral prazosin on blood pressure, plasma active renin and angiotensin II in 16 recumbent hypertensive patients between 09.00 and 12.00 hours. 2. In untreated patients there were no significant changes in blood pressure, plasma active renin or angiotensin II during the 3 h period. 3. After an initial dose of prazosin (2 mg) there was a significant fall in recumbent blood pressure with progressive increases in plasma active renin and angiotensin II concentrations. 4. After 3--4 weeks' treatment with oral prazosin only, recumbent blood pressure at 09.00 hours, 15 h after the last dose of prazosin, was significantly lower than before treatment, but plasma active renin and angiotensin II were not significantly different from untreated values. 5. After the usual morning dose of prazosin, blood pressure did not change, but there were significant rises in plasma active renin and angiotensin II, less marked than after the first dose of prazosin. 6. Prazosin therefore stimulates the renin--angiotensin system acutely, both after the initial dose and during long-term therapy; however, no effect on renin and angiotensin II is apparent 15 h after the last dose of prazosin.

Administration, Oral↗
PubMed1978

Aspergillosis of the central nervous system.

Aspergillosis of the central nervous system is rare. The spread to the CNS is usually from the lungs and uncommonly from paranasal sinuses. Four cases of CNS aspergillosis with spread of infection from the paranasal sinuses are described. Two patients had meningitis, one intracranial granuloma and one presented with subarachnoid haemorrhage resulting from a fungal mycotic aneurysm. Difficulties in establishing the diagnosis are discussed.

Adolescent↗
PubMed1976

Myiasis in otorhinolaryngology with entomological aspects.

Maggot infestation in a series of 100 cases pertaining to the E.N.T. domain is reported. The Entomological aspects were studied in 20 cases. The clinical features of myiasis have been described. This disease commonly occurs in diseased nasal and ear cavities which allow maggots to grow. The use of maggot oil drops and irrigation with normal saline provides an effective treatment. Prevention of maggot infestation is stressed.

Adolescent↗
PubMed1975

Desmoplastic fibroma of maxilla.

Desmoplastic fibroma of the long bones is very rare and has been mentioned in the literature, but there is no mention in the literature of desmoplastic fibroma occurring in relation to maxilla. The first case of desmoplastic fibroma of the maxilla is reported. Conservative surgery is recommended for desmoplastic fibroma of the maxilla to avoid facial deformity.

Adult↗