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Biomedical subjects

V P Mital

Publications and source records attributed to V P Mital.

At least 19 recordsLinked to original sources
PubMed1994

Effect of low intensity laser radiation on healing of open skin wounds in rats.

Two full thickness skin wounds were produced on either side of dorsal midline in rats to study the effect of low intensity laser radiation on wound healing. Wounds on left side were irradiated daily with Helium Neon laser at 4 Joules/sq cm for 5 min. Wounds on right side were not exposed and served as controls. The mean +/- SD of time required for complete closure in control group was 14.1 +/- 0.86 days (range 12-15 day) while irradiated test wounds took only 10.3 +/- 0.68 days (range 9-12 days) to heal (P < 0.001). Granulation tissue was significantly (P < 0.001) more in test than in control wounds. Early epithelisation with increased fibroblastic reaction, leukocytic infiltration and neo vascularisation was seen in the laser irradiated wounds. The collagen hydroxyproline concentration of scar tissue was also significantly higher (P < 0.001) in test group on 17th post-operative day. The study establishes the biostimulatory effects of low intensity laser radiation on healing of skin wounds.

Animals↗
PubMed1991

Fibrinolysis in idiopathic menorrhagia.

Serum fibrin/fibrinogen degradation product (FDP) was studied in 64 patients of menorrhagia without any organic cause in addition to 24 healthy women by Thrombo - Wellcotest HA - 13 Kit (Wellcome, England). Serum FDP levels were found to be less than 10 micrograms/ml in healthy subjects, whereas in idiopathic menorrhagia it was more than 10 micrograms/ml in 59.34% patients. Semi-quantitative estimation of FDP in 14 patients of idiopathic menorrhagia indicated a positive correlation between duration of bleeding and FDP levels. Bleeding appears to be due to increased fibrinolytic activity in uterus secondary to plasminogen activator. Such patients are likely to be benefitted with anti-fibrinolytic agents.

Female↗
PubMed1983

Status of T and B lymphocytes in peripheral blood.

T and B lymphocyte percentage was studied by Erythrocyte (E) and Erythrocyte antibody complement (EAC) rosette formation respectively in 90 cases including 65 cases of different types of leprosy and 25 healthy controls. The patient with different types of leprosy were classified according to Ridley and Jopling (1962). The mean percentage of T-lymphocyte was observed in gradually decreasing manner from tuberculoid pole to lepromatous pole. The fall in T-lymphocyte percentage was highly significant when control cases were compared with total cases of leprosy and different histological types of leprosy. This indicates that there is a gradually increasing loss of cell mediated immune response from tuberculoid to lepromatous pole.

Adolescent↗