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Biomedical subjects

V P Kotel'nikov

Publications and source records attributed to V P Kotel'nikov.

At least 19 recordsLinked to original sources
PubMed1996

[The blood coagulating activity in burns].

Data obtained in experiments in 80 rats and in clinical observations of 24 patients with burns of the II and IIIA degrees showed the activation of vasculo-thrombocytic and procoagulant links of the hemostasis system with a simultaneous depression of the anticoagulative blood system. The thermal trauma is followed by a dramatic decrease of the concentration of heparin, fibrinogen, decreased activity of antithrombin-III, fibrinolysis and plasminogen activators. There was a simultaneous growth of concentration of antiplasmins (alpha 2-macroglobulin and alpha 1-antitrypsin).

Adult↗
PubMed1990

[Neurohumoral regulation in frostbite].

The article presents experimental and clinical data on changes of homeostasis in frostbites. It is shown that the zone of injured tissues can be lessened by acting the mechanism of neurohumoral regulation with rausedyl, heparin and fibrinolysin.

Acetylcholine↗
PubMed1989

[Lymphangitis].

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Combined Modality Therapy↗
PubMed1989

[Suppurative wounds].

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Combined Modality Therapy↗
PubMed1989

[Hemostatic changes after local exposure to low temperatures (frostbite)].

Hemostatic blood potential was studied in experiments on 400 rats, 25 dogs and in 120 patients, during changes of CNS reactivity after intraventricular injection of reserpine, adrenaline, and irritation of the thalamus ventromedial nucleus (VMN) or its destruction. CNS reactivity in dogs changed after intraarterial injections of acetylcholine, reserpine, heparin and fibrinolysin solutions. It was shown that activation of adrenergic structures of the hypothalamus by intraventricular adrenaline injections, or the hypothalamus VMN irritation, stimulated coagulation and depressed anticoagulation mechanisms of the blood, and increased hemostatic blood potential, that led to rejection of frostbitten tissues. Activation of the hypothalamus cholinergic structures by intraventricular injections of reserpine, destruction of the hypothalamus VMN, and intraarterial injections of acetylcholine, reserpine, heparin, fibrilysin and contrycal mixtures stimulated the blood anticoagulation mechanisms, decreased the hemostatic potential, led to retention of cryodestructed tissues.

Animals↗