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Biomedical subjects

V P Filippov

Publications and source records attributed to V P Filippov.

At least 19 recordsLinked to original sources
PubMed1995

[Use of bronchovaxom in the treatment of patients with chronic obstructive bronchitis and bronchial asthma].

Polyvalent vaccine bronchovaxom (BV) was studied for efficacy against chronic obstructive bronchitis and bronchial asthma exacerbation. Good results were reported: reduction of disability duration, number of recurrences, cough intensity, discharged sputum. Laboratory tests discovered that BV brought about IgE decrease, IgA, T3, T4/T8 increase in bronchoalveolar lavage.

Adjuvants, Immunologic↗
PubMed1991

[Effectiveness of the use of high-energy lasers in bronchology].

Bronchoscopy by laser radiation was performed in 141 patients. CO2 laser was used in 89 patients: 25 had pulmonary tuberculosis, 6 tumours, 35 stump inflammation, and 23 other diseases. YAG laser was used in 52 patients: 15 of them had tumours, 21 bronchial tuberculosis, 6 osteochondropathy and 10 other diseases. A good therapeutic result was obtained in most patients but in certain cases (malignant tumours) it was palliative. Special features and technical difficulties encountered during work with different types of lasers in fibroscopy under anesthesia and in fibrobronchoscopy under local narcosis are discussed. No complications were registered. Formation of the so-called "white thrombus" at the site of laser photodestruction was described which required removal during control bronchoscopy.

Bronchial Diseases↗
PubMed1991

[The status of mucociliary clearance in patients with pulmonary tuberculosis].

The authors present the findings of mucociliary clearance (MCC) in 64 patients, including 45 with different forms of pulmonary tuberculosis and 19 with chronic nonspecific pulmonary diseases. MCC was determined with the radioaerosol method with the use of TCK-5 kit human albumin suspension and 99mTc radioisotope. Fibrobronchoscopy was performed in all the patients and a brush bronchial mucosa biopsy in 34 of them. MCC indices in patients with different pulmonary diseases were analysed. The obtained data were compared with the status of the bronchial epithelium from cytologic study of bronchial biopsy specimens. A relationship of MCC drop in case of pathology in the bronchial villous apparatus was revealed.

Adolescent↗
PubMed1989

[Use of the CO2 laser in endobronchial pathology].

Endoscopic therapy by CO2-laser of the "Skalpel-1" type through the Friedel breathing bronchoscope is analyzed. The treatment was performed in 40 patients with various endobronchial affections such as tumors, fistulas due to tuberculosis of the intrathoracic lymph nodes, specific and nonspecific stump inflammation, mycotic lesions of the stump mucosa, foreign bodies, cicatricial stenosis of the bronchi, scleroma of the trachea and bronchi, hemorrhage. High efficiency of endoscopic laser bronchoscopy was shown.

Aged↗
PubMed1989

[The etiologic significance of ultrafine forms of the causative agent of tuberculosis in the development of sarcoidosis of the respiratory organs].

Pathological material, i. e. bronchoalveolar lavage fluid (BALF) and blood plasma from patients with various pathological processes in the lungs was studied. Eighty seven patients with sarcoidosis of the respiratory organs were subjected to complex microbiological investigation and ultrasmall forms of tubercle bacilli were detected in BALF of 67 (77 per cent) of them. Histological examination revealed alveolitis and granulomas of lymphoid-macrophagal nature in the lungs of the experimental animals exposed to the material from the sarcoidosis patients.

Female↗
PubMed1989

[The instrumental diagnosis of disseminated lesions of the lungs].

A study is presented of 52 patients with disseminated pulmonary lesions. Among them: histiocytosis X--17, alveolar microlithiasis--5, pulmonary phospholipoproteinosis--7, idiopathic hemosiderosis--14, primary pulmonary amyloidosis--1, primary diffuse lung tumours--8. All patients were subjected to complex bronchological examination including use of different biopsy transbronchial methods as well as open biopsy of the lung. The diagnostic value of the employed bronchial biopsies is discussed. A diagnostic algorithm of rarely met pulmonary disseminations has been developed. Recommendations on the use of different instrumental methods are formulated.

Adolescent↗
PubMed1989

[Use of carbon dioxide laser in the treatment of tuberculosis of the bronchi and trachea in children and adolescents].

The first experience with using carbon laser in treatment of specific bronchial affections in children and adolescents was studied. Persisting lymphobronchial fistulas and granulations in 4 children and adolescents were considered as indications to the treatment. The 2-3 exposures, to laser during bronchoscopy with burning out the granulations and caseous led to rapid healing of the fistulas and epithelization of the bronchial surface with formation of small cicatrices. No complications were observed.

Adolescent↗