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Biomedical subjects

V P Barranco

Publications and source records attributed to V P Barranco.

15 recordsLinked to original sources
PubMed1998

Clinically significant drug interactions in dermatology.

Access to information on clinically significant drug interactions is not readily available. This can be a source of uncertainty, and locating this information can be tedious and time-consuming. The pharmacology of drug interactions is briefly discussed. The most common drug interactions involve altered hepatic metabolism. At least 26 drugs are such frequent offenders that they can be considered "red flag" drugs. In addition, an extensive list of current significant and less significant drug interactions of particular importance to the dermatologist is presented.

Cytochrome P-450 Enzyme System↗
PubMed1985

Multiple benign lichenoid keratoses simulating photodermatoses: evolution from senile lentigines and their spontaneous regression.

Evidence from several studies has established that a solitary benign lichenoid keratosis evolves from a senile lentigo. This lesion tends to resolve spontaneously with partial or complete regression of the original senile lentigo. In a 2-year period we studied fourteen patients with multiple benign lichenoid keratoses simulating photodermatoses. The original two patients were thought initially to have either cutaneous lupus erythematosus or a drug-induced photodermatitis. All fourteen patients were found to have multiple benign lichenoid keratoses distributed primarily in sun-exposed skin and arising from preexisting senile lentigines. The lichenoid lesions disappear either with topical corticosteroid treatment or spontaneously and are followed by partial or complete regression of the original senile lentigines. This disease entity seems to be fairly common and may be easily confused with photodermatoses.

Adult↗
PubMed1976

Treatment of relapsing polychondritis with dapsone.

Three patients with relapsing polychondritis were treated successfully with dapsone. Mounting evidence suggests an immune-related pathogenesis for relapsing polychondritis. Dapsone may be effective in certain immune-related diseases because of its inhibition of lysosomal enzymes.

Aged↗