[The vascular and thrombocytic components of the hemostasis system in acute blood loss and its correction].
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Biomedical subjects
Publications and source records attributed to V P Baluda.
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The paper is concerned with the data on the arteriovenous difference in antithrombin III activity and antiaggregation properties of the aortal and inferior vena cava walls in Wistar rats. A correlation between the changes identified and different thromboresistance of the arteries and veins is suggested.
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The influence of gamma-rays 60Co and fast neutrons on intravascular platelet aggregation and prostacyclin activity of the vascular wall has been studied. It has been shown that 1-6 hours after irradiation of CBA mice, a great number of bone marrow platelets clump to form fibrin fibrils that often close completely the vascular lumen. Experiments with irradiated rats and guinea-pigs have demonstrated the reduction of prostacyclin-like activity in the abdominal aorta wall.
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The blood of 100 health humans aged 18 to 40 years was analysed. The aggregation of platelets and blood fibrinolytic activity were shown to change within 23-day physical cycle according to Swoboda and Fliess. In the negative phase the platelets count, their aggregation, desaggregation process and blood fibrinolytic activity were higher than in the positive one. No substantial differences in platelets aggregation and blood fibrinolytic activity were found during the positive and negative phases of the emotional or intellectual cycles.
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