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Biomedical subjects

V Ottani

Publications and source records attributed to V Ottani.

32 records · Page 2Linked to original sources
PubMed1988

Effects of pulsed extremely-low-frequency magnetic fields on skin wounds in the rat.

Rats with skin-wounds surgically created on their backs were exposed immediately after surgery and every 12 h thereafter to pulsed, extremely-low-frequency magnetic fields. The shape of the pulse was a positive triangle (50 Hz, 8 mT peak). The rate of healing of skin wounds was evaluated macroscopically and by light and electron microscopy at 6, 12, 21, and 42 days after the operation. A significant increase in the rate of wound contraction was found in rats treated with magnetic fields. Forty-two days after surgery all treated animals show fully closed wounds, while control rats at the same time intervals still lacked a final 6% of the wound surface to be covered. Treated rats showed earlier cellular organization, collagen formation and maturation, and a very early appearance of newly formed vascular network.

Animals↗
PubMed1984

Pulsed electromagnetic fields increase the rate of rat liver regeneration after partial hepatectomy.

Pulsed extremely low-frequency electromagnetic fields interact with rat liver regeneration following partial hepatectomy when delivered to the rats immediately after the operation and every 12 hr thereafter. This interaction results first in an increased ornithine decarboxylase activity, an enzyme used as an early marker of cell growth. The rate of labeled thymidine incorporation into DNA is also increased by the treatments with magnetic fields during the early phases of liver regeneration. Glycogen depletion and lipid accumulation, two well-known early peculiar phenomena of liver regeneration following partial hepatectomy, are quantitatively decreased by the treatments with electromagnetic fields. The recovery to normal glycogen and lipid contents is completed within 5 days after surgery, instead of 7 days as found in control rats.

Animals↗
PubMed1984

Influence of pulsed electromagnetic fields on regenerating rat liver after partial hepatectomy.

Partially hepatectomised rats have been exposed immediately after surgery and every 12 hours thereafter to pulsed extremely low frequency electromagnetic fields. Stereological analysis performed on electron micrographs has shown that the treatment limits the depletion of liver glycogen found in control untreated rats within the first post-operative day. The massive accumulation of lipid droplets found in control rats is also limited to about one half by exposing the animals to pulsed magnetic fields. The time taken for glycogen and lipid content to recover to values found at zero time decreases from seven to five days in animals undergoing treatment with pulsed electromagnetic fields. The liver wet weight and the total protein content show a pattern of changes which is consistent with the behaviour of glycogen and lipid content. Five days after operation the treated rats reach the values found at zero time, while control animals need seven days to reach the same values.

Animals↗
PubMed1982

[Ultrastructural findings on collagen fibers of tendon sheaths from the rat tail].

Rat tail tendon sheaths have been studied by electron microscopy and freeze-etching techniques. Pictures from thin sections have shown the presence of three different sheaths: a) a sheath commun to all tendons, (paratenon) formed by collagen fibrils differently orientated with a variable diameter (20nm 200nm) b) a specific sheath for every tendon, (peritenoneum) which is composed by different layers: the external ones present collagen fibrils of wide and variable diameter (20nm-200nm). The internal ones present collagen fibrils of uniform and small diameter (50nm-60nm). Between these fibres layers, there is evidence for the presence of fibrocits forming continuous cellular layers. c) a sheath surrounding tendon fascicles, (endotenoneum) formed by small and uniform collagen fibrils and a continuous cellular layers. Replicas of freeze-fractured collagen fibrils having a variable diameter show a straight arrangement of their microfibrils.

Animals↗